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논문 기본 정보

자료유형
학술저널
저자정보
Sang Yoon Kim (Department of Internal Medicine Myongji Hospital Hanyang University College of Medicine) Su Jin Kim (Department of Internal Medicine Pusan National University Yangsan Hospital Pusan National University School of Medicine) Ayoung Lee (Department of Internal Medicine College of Medicine Ewha Womans University) Kichul Yoon (Department of Internal Medicine Seonam Hospital) Jun Young Park (Department of Internal Medicine Seoul St. Mary’s Hospital College of Medicine The Catholic University of Korea) Ju Yup Lee (Department of Internal Medicine Keimyung University School of Medicine Daegu Korea) Jae Myung Park (Department of Internal Medicine Seoul St. Mary’s Hospital College of Medicine The Catholic University of Korea)
저널정보
대한상부위장관 헬리코박터학회 Korean Journal of Helicobacter Upper Gastrointestinal Research Korean Journal of Helicobacter Upper Gastrointestinal Research Vol.23 No.1
발행연도
2023.3
수록면
52 - 62 (11page)

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Background/Aims: Transcatheter arterial embolization (TAE) is useful for management of uncontrolled upper gastrointestinal (UGI) bleeding. We investigated clinical outcomes of TAE for non-variceal bleeding from benign UGI diseases uncontrolled with endoscopic intervention. Methods: This retrospective study performed between 2017 and 2021 across four South Korean hospitals. Ninety-two patients (72 men, 20 women) who underwent angiography were included after the failure of endoscopic intervention for benign UGI disease- induced acute non-variceal bleeding. We investigated the factors associated with endoscopic hemostasis failure, the technical success rate of TAE, and post-TAE 30-day rebleeding and mortality rates. Results: The stomach (52/92, 56.5%) and duodenum (40/92, 43.5%) were the most common sites of bleeding. Failure of endoscopic procedures was attributable to peptic ulcer disease (81/92, 88.0%), followed by pseudo-aneurysm (5/92, 5.4%), and angiodysplasia (2/92, 2.2%). Massive bleeding that interfered with optimal visualization of the endoscopic field was the most common indication for TAE both in the stomach (22/52, 42.3%) and duodenum (14/40, 35.0%). Targeted TAE, empirical TAE, and exclusive arteriography were performed in 77 (83.7%), nine (9.8%), and six patients (6.5%), respectively. The technical success rate, the post-TAE 30-day rebleeding rate, and the overall mortality rate were 100%, 22.1%, and 5.8%, respectively. On multivariate analysis, coagulopathy (OR, 5.66; 95% CI, 1.71~18.74; P=0.005) and empirical embolization (OR, 5.71; 95% CI, 1.14~28.65; P=0.034) were independent risk factors for post-TAE 30-day rebleeding episodes. Conclusions: TAE may be useful for acute non-variceal UGI bleeding. Targeted embolization and correction of coagulopathy can improve clinical outcomes.

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