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논문 기본 정보

자료유형
학술저널
저자정보
Jung Jang Han (Division of Gastroenterology Department of Internal Medicine Hallym University Dongtan Sacred Heart) Jo Jung Hyun (Division of Gastroenterology Department of Internal Medicine Yonsei University College of Medicine) Kim Sung Eun (Division of Gastroenterology Department of Internal Medicine Hallym University Sacred Heart Hospita) Bang Chang Seok (Division of Gastroenterology Department of Internal Medicine Hallym University Chuncheon Sacred Hea) Seo Seung In (Division of Gastroenterology Department of Internal Medicine Gangdong Sacred Heart Hospital Seoul K) Park Chan Hyuk (Department of Internal Medicine Hanyang University Guri Hospital Hanyang University College of Medi) Park Se Woo (Division of Gastroenterology Department of Internal Medicine Hallym University Dongtan Sacred Heart)
저널정보
거트앤리버 발행위원회 Gut and Liver Gut and Liver 제16권 제1호
발행연도
2022.1
수록면
101 - 110 (10page)
DOI
10.5009/gnl20375

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Background/Aims: The appropriate number of band ligations during the first endoscopic session for acute variceal bleeding is debatable. We aimed to compare the technical aspects of endoscopic variceal ligation (EVL) in patients with variceal bleeding according to the number of bands placed per session. Methods: We retrospectively reviewed multicenter data from patients who underwent EVL for acute variceal bleeding. Patients were classified into minimal EVL (targeting only the foci with active bleeding or stigmata of recent bleeding) and maximal EVL (targeting potential bleeding sources in addition to the aforementioned targets) groups. The primary endpoint was 5-day treatment failure. The secondary endpoints were 30-day rebleeding, 30-day mortality, and intraprocedural adverse events. Results: Minimal EVL was associated with lower rates of hypoxia and shock during EVL than maximal EVL (hypoxia, 0.9% vs 2.9%; shock, 1.3% vs 3.4%). However, treatment failure was higher in the minimal EVL group than in the maximal EVL group (odds ratio, 1.60; 95% confidence interval, 1.06 to 2.41). Age ≥60 years, Model for End-Stage Liver Disease score ≥15, Child-Turcotte-Pugh classification C, presence of hepatocellular carcinoma, and systolic blood pressure <90 mm Hg at initial presentation were also associated with treatment failure. In contrast, 30-day rebleeding and 30-day mortality did not differ between the minimal and maximal EVL groups. Conclusions: Given that minimal EVL was associated with a high risk of treatment failure, maximal EVL may be a better option for variceal bleeding. However, the minimal EVL strategy should be considered in select patients because it does not affect 30-day rebleeding and mortality.

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