갑상선 유두상 미세암종의 임상적 특징

김재원; 이동율; 조영업; 김창효; 오윤석; 김영모

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자료유형: 학술저널

저자정보: 김재원 이동율 조영업 김창효 오윤석 김영모

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제53권 제3호

발행연도: 2010.1

수록면: 166 - 171 (6page)

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Background and ObjectivesZZMost papillary thyroid microcarcinoma (PTMC) carry a favorable prognosis, but a few patients present with aggressiveness. We classified PTMC according to the tumor size, and investigated the treatment, pathological finding and clinical behavior. Subjects and MethodZZOut of 714 patients submitted to surgical treatment for well differentiated thyroid cancer between 1996 and 2006, 179 (25%) patients had been identified as PTMC. These records were reviewed retrospectively, and followed up for 4 to 114 months (mean 43.3months). ResultsZZThe incidentaloma was 53 from 179 PTMC. The surgical procedures were hemithyroidectomy (n=79) or total thyroidectomy (n=100) including completion thyroidectomy. In the pathologic finding, 46 cases (25%) had extrathyroidal extensions and 37 cases (20%) had lymph node metastasis. In the total thyroidectomy cases, 35 cases had multiplicity, including 18 bilateral cases. When mass sizes were divided into those either bigger or smaller than 5 mm, statistical significance was found only in the extrathyroidal extensions (p=0.023). There were 2 recurrences in the total thyroidectomy cases and 4 in hemithyroidectomy, but without any statistical difference. With respect to size, there was only 1 recurrence in patients whose mass size was smaller than 5 mm and 5 in patients whose mass size was bigger than 5 mm; there was no statistical difference, however. ConclusionZZPathologically, extrathyroidal extension was more common in cases with tumor size more than 5 mm. This finding could be the evidence of poorer prognosis in these cases. However,there was no difference in the recurrence rate between the groups of different sizes and thyroidectomy methods. Therefore, surgical options should be carefully decided in the treatment of PTMC. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:166-71

#Thyroidectomy·Papillary thyroid cancer·Recurrence.

참고문헌 (15)

참고문헌 신청

Appetecchia M / 2002 / Outcome after treatment of papillary thyroid microcarcinoma / J Exp Clin Cancer Res 21 (2) : 159 ~ 164

Baudin E / 1998 / Microcarcinoma of the thyroid gland: the Gustave-Roussy Institute experience / Cancer 83 (3) : 553 ~ 559

Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 (1) : 31 ~ 40

Dietlein M / 2005 / Incidental multifocal papillary microcarcinomas of the thyroid: is subtotal thyroidectomy combined with radioiodine ablation enough? / Nucl Med Commun 26

Hay ID / 1992 / Papillary thyroid microcarcinoma: A study of 535 cases observed in a 50-year period / Surgery 112 (6) : 1139 ~ 1146

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