20세 이하 갑상선 유두암 환자의 임상 특징과 치료 결과

박성호; 최주열; 김남영; 김경헌; 이국행; 이병철; 이명철; 최익준

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자료유형: 학술저널

저자정보: 박성호 최주열 김남영 김경헌 이국행 이병철 이명철 최익준

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제58권 제11호

발행연도: 2015.1

수록면: 764 - 768 (5page)

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Background and Objectives Thyroid carcinoma rarely occurs in children and adolescents, whose clinical features are diverse, and treatment outcomes are still controversial. The aim of this study was to evaluate the clinical features and the treatment outcomes of papillary thyroid carcinoma (PTC) patients younger than 20 years old. Subjects and Method This is a retrospective study for patients younger than 20 years old, who were diagnosed as PTC from January 1992 to February 2009. Clinical features, size, pathologic type, extrathyroidal extension, recurrence, multiplicity, extent of surgery, and lymph node metastasis were retrospectively evaluated. Results Forty patients, of 6 malse and 34 females, were enrolled, with their mean age being 16 years old. The initial operations were total thyroidectomy for 9 patients, unilateral lobectomy for 15 patients, and total thyroidectomy and lateral neck dissection for 16 patients. Cervical lymph node metastases were diagnosed in 25 patients. Extrathyroidal extensions were observed in 30 patients. Postoperative radioactive iodine therapy was performed in 35 patients. During the follow-up period, 8 patients had recurred. All patients were alive at the last follow-up. Conclusion PTC in children and adolescents aged under 20 is a rare disease and tends to present as an advanced disease with low mortality compared to adult PTC. Recurrence had no effect on survival. Aggressive treatment with total thyroidectomy, central neck dissection, and radioiodine therapy may prevent recurrence.

#Adolescent #Children #Papillary thyroid carcinoma

참고문헌 (16)

참고문헌 신청

Brink JS / 2000 / Papillary thyroid cancer with pulmonary metastases in children: long-term prognosis / Surgery 128 (6) : 881 ~ 886

Frankenthaler RA / 1990 / Lymph node metastasis from papillary-follicular thyroid carcinoma in young patients / Am J Surg 160 (4) : 341 ~ 343

Grigsby PW / 2002 / Childhood and adolescent thyroid carcinoma / Cancer 95 (4) : 724 ~ 729

Harness JK / 1992 / Differentiated thyroid carcinoma in children and adolescents / World J Surg 16 (4) : 547 ~ 553

Haveman JW / 2003 / Surgical experience in children with differentiated thyroid carcinoma / Ann Surg Oncol 10 (1) : 15 ~ 20

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