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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.9
- 수록면
- 156 - 161 (6page)
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이 논문의 연구 히스토리 (4)
2010
2009
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Purpose: The aim of this study was to analyze the relationship between central lymph node metastasis and the associated factors in patients with papillary thyroid carcinoma (PTC) according to the tumor size, and we wanted to determine an appropriate treatment for PTC.
Methods: From June 2005 to May 2007, 218 patients with PTC underwent total thyroidectomy or lobectomy, and they also received central lymph node dissection at our institution. The patients were divided into three groups: group 1 (tumor ≤5 ㎜), group 2 (5 ㎜＜tumor≤10 ㎜), and group 3 (tumor＞10 ㎜). We retrospectively reviewed these patients to analyze the relationship between tumor size and the clinicopathological characteristics, including age, gender, lymph node metastasis, extrathyroidal extension, capsular invasion and lymphovascular invasion.
Results: There were 47 (21.6%) patients in group 1, 101 (46.3%) patients in group 2 and 70 (32.1%) patients in group 3. The tumor size was closely correlated with the presence of extrathyroidal extension, capsular invasion and lymph node metastasis (P＜0.001). Lymph node metastasis was not only closely correlated with tumor size, but it was also significantly associated with extrathyroidal extension, capsular invasion and lymphovascular invasion (P＜0.05).
Conclusion: Our study confirmed that some factors, including central lymph node metastasis, capsular invasion and extrathyroidal extension, were frequently observed in patients with papillary thyroid microcarcinoma (PTMC), and central lymph node metastasis was related to tumor size, extrathyroidal extension, capsular invasion and lymphovascular invasion. Therefore, routine central lymph node dissection is reco㎜ended during the initial surgery for patients with PTMC.
Methods: From June 2005 to May 2007, 218 patients with PTC underwent total thyroidectomy or lobectomy, and they also received central lymph node dissection at our institution. The patients were divided into three groups: group 1 (tumor ≤5 ㎜), group 2 (5 ㎜＜tumor≤10 ㎜), and group 3 (tumor＞10 ㎜). We retrospectively reviewed these patients to analyze the relationship between tumor size and the clinicopathological characteristics, including age, gender, lymph node metastasis, extrathyroidal extension, capsular invasion and lymphovascular invasion.
Results: There were 47 (21.6%) patients in group 1, 101 (46.3%) patients in group 2 and 70 (32.1%) patients in group 3. The tumor size was closely correlated with the presence of extrathyroidal extension, capsular invasion and lymph node metastasis (P＜0.001). Lymph node metastasis was not only closely correlated with tumor size, but it was also significantly associated with extrathyroidal extension, capsular invasion and lymphovascular invasion (P＜0.05).
Conclusion: Our study confirmed that some factors, including central lymph node metastasis, capsular invasion and extrathyroidal extension, were frequently observed in patients with papillary thyroid microcarcinoma (PTMC), and central lymph node metastasis was related to tumor size, extrathyroidal extension, capsular invasion and lymphovascular invasion. Therefore, routine central lymph node dissection is reco㎜ended during the initial surgery for patients with PTMC.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (29)
참고문헌 신청
1. [학술지(정기간행물)] - Zuo H / 2007 / A review of 227 cases of small papillary thyroid carcinoma / Eur J Surg Oncol 33 : 370 ~ 375
2. [학술지(정기간행물)] - Cooper DS / 2006 / Management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 16 : 109 ~ 142
3. [학술지(정기간행물)] - Hedinger C / 1989 / The WHO histological classification of thyroid tumors: a commentary on the second edition / Cancer 63 : 908 ~ 911
4. [학술지(정기간행물)] - Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
5. [학술지(정기간행물)] - Renshaw AA / 2005 / Papillary carcinoma of the thyroid ＜or=1.0 cm: rarely incidental or occult any more / Cancer 105 : 217 ~ 219
2. [학술지(정기간행물)] - Cooper DS / 2006 / Management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 16 : 109 ~ 142
3. [학술지(정기간행물)] - Hedinger C / 1989 / The WHO histological classification of thyroid tumors: a commentary on the second edition / Cancer 63 : 908 ~ 911
4. [학술지(정기간행물)] - Chow SM / 2003 / Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality / Cancer 98 : 31 ~ 40
5. [학술지(정기간행물)] - Renshaw AA / 2005 / Papillary carcinoma of the thyroid ＜or=1.0 cm: rarely incidental or occult any more / Cancer 105 : 217 ~ 219
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UCI(KEPA) : I410-ECN-0101-2013-514-002689943