지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 59 - 62 (4page)
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초록· 키워드
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Clinical interpretation of the test results for cortisol based on continuous reference intervals with appropriate partitions improves pediatric diagnosis; however, these values are available only for Caucasians. To develop the pediatric reference intervals for Chinese population, we examined the serum cortisol levels in 1,143 healthy Chinese children aged 4–18 years (566 boys and 577 girls), using an IMMULITE 2000 Immunoassay System (Siemens Healthcare GmbH). Phlebotomy was performed at 7–9 a.m. for 284 boys and 287 girls and at 1–3 p.m. for the others. They were divided into four age groups according to the Clinical and Laboratory Standards Institute guideline EP28-A3c, with the last group further stratified according to sampling time. Separate reference intervals of 49.6–323.7, 70.9–395.3, and 90.1–448.7 nmol/L were established for children aged 4–8, 9–12, and 13–15 years, respectively. Further, reference intervals of 118.2–464.7 and 71.4–446.7 nmol/L were established for morning and afternoon cortisol levels, respectively, in children aged 16–18 years. Further studies are necessary to transfer and validate these reference intervals in other analytical systems and pediatric populations, and to allow for broader applications.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
de Kloet ER / 2008 / Everything has rhythm: focus on glucocorticoid plusatility / Endocrinol 149:3241~3243
Rovnaghi CR / 2014 / Interpretation of cortisol concentrations and reference intervals from the CALIPER database / Clin Chem 60:418~419
Karbasy K / 2015 / Advances in pediatric reference intervals for biochemical markers: Establishment of the CALIPER database in healthy children and adolescents / J Med Biochem 34:23~30
CLSI / 2008 / Defining, establishing, and verifying reference intervals in the clinical laboratory; approved guideline - third edition. CLSI document EP28-A3c / Clinical and Laboratory Standards Institute :8~28
Group of COTF / 2004 / The body mass index reference norm for screening overweight and obesity in Chinese children and adolescents / Chin J Epidemiol 25:97~102
Rovnaghi CR / 2014 / Interpretation of cortisol concentrations and reference intervals from the CALIPER database / Clin Chem 60:418~419
Karbasy K / 2015 / Advances in pediatric reference intervals for biochemical markers: Establishment of the CALIPER database in healthy children and adolescents / J Med Biochem 34:23~30
CLSI / 2008 / Defining, establishing, and verifying reference intervals in the clinical laboratory; approved guideline - third edition. CLSI document EP28-A3c / Clinical and Laboratory Standards Institute :8~28
Group of COTF / 2004 / The body mass index reference norm for screening overweight and obesity in Chinese children and adolescents / Chin J Epidemiol 25:97~102
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