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논문 기본 정보

자료유형
학술저널
저자정보
Sung Ji Yeon (Department of Laboratory Medicine Seoul National University Hospital and College of Medicine Seoul) Seo Jong Do (Department of Laboratory Medicine Seoul National University Hospital and College of Medicine Seoul) Ko Dae-Hyun (Department of Laboratory Medicine University of Ulsan College of Medicine and Asan Medical Center S) Park Min-Jeong (Department of Laboratory Medicine Kangnam Sacred Heart Hospital Hallym University College of Medici) Hwang Sang Mee (Department of Laboratory Medicine Seoul National University Bundang Hospital Seongnam Korea) Oh Sohee (Department of Biostatistics Seoul Metropolitan Government Seoul National University Boramae Medical) Chun Sail (Department of Laboratory Medicine University of Ulsan College of Medicine and Asan Medical Center S) Seong Moon-Woo (Department of Laboratory Medicine Seoul National University Hospital and College of Medicine Seoul) Song Junghan (Department of Laboratory Medicine Seoul National University Hospital and College of Medicine Seoul) Song Sang Hoon (Department of Laboratory Medicine Seoul National University Hospital and College of Medicine Seoul) Park Sung Sup (Department of Laboratory Medicine Seoul National University Hospital and College of Medicine Seoul)
저널정보
대한진단검사의학회 Annals of Laboratory Medicine Annals of Laboratory Medicine 제41권 제2호
발행연도
2021.1
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155 - 170 (16page)

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Background: Reference intervals defined for adults or children of other ethnicities cannot be applied in the evaluation of Korean pediatric patients. Pediatric reference intervals are difficult to establish because children are in their growing stage and their physiology changes continuously. We aimed to establish reference intervals for routine laboratory tests for Korean pediatric patients through retrospective multicenter data analysis. Methods: Preoperative laboratory test results from 1,031 pediatric patients aged 0 month?18 years who underwent minor surgeries in four university hospitals were collected. Age- and sex-specific reference intervals for routine laboratory tests were defined based on the Clinical and Laboratory Standards Institute (CLSI) EP28-A3c guidelines. Results: The pediatric reference intervals determined in this study were different from existing adult reference intervals and pediatric reference intervals for other ethnicities. Most tests required age-specific partitioning, and some of those required sex-specific partitioning for at least one age-partitioned subgroup. Erythrocyte sedimentation rate, monocyte percentage, basophil percentage, activated partial thromboplastin time, glucose, cholesterol, albumin, bilirubin, chloride, and C-reactive protein did not show any difference between age- or sex-partitioned subgroups. Conclusions: We determined Korean pediatric reference intervals for hematology, coagulation, and chemistry tests by indirect sampling based on medical record data from multiple institutions. These reference intervals would be valuable for clinical evaluations in the Korean pediatric population.
#Reference intervals #Indirect sampling #Korean pediatrics #Age-partitioned groups #Sex-partitioned groups #Multicenter

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참고문헌 (36)

참고문헌 신청
Horn PS / 2003 / Reference intervals: an update / Clin Chim Acta 334:5~23 google schola CLSI / 2010 / Defining, establishing, and verifying reference intervals in the clinical laboratory; approved guideline / Clinical Laboratory Standards Institute google schola Jung B / 2009 / Clinical laboratory reference intervals in pediatrics:the CALIPER initiative / Clin Biochem 42:1589~1595 google schola Schnabl K / 2008 / 3. Pediatric reference intervals: critical gap analysis and establishment of a national initiative / EJIFCC 19:115~122 google schola Schnabl K / 2008 / Closing the gaps in paediatric reference intervals: the CALIPER initiative / Clin Biochem Rev 29:89~96 google schola

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