지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제5권 제6호
- 발행연도
- 2017.1
- 수록면
- 336 - 343 (8page)
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초록· 키워드
오류제보하기
Purpose: Ultrarush immunotherapy (ultra-RIT) is more convenient and higher compliant than conventional immunotherapy, but it has rarely used in clinical practice due to severe systemic reactions. This study aimed to determine the safety of ultra-RIT in children and adolescents.
Methods: We investigated 19 patients who received ultra-RIT with the same schedule between January 2011 and May 2016. They were sensitized to house dust mites (HDMs) and/or pollen and had their symptoms associated with positive allergens. Over a 1-day hospitalization period, all patients received ultra-RIT subcutaneously 3 times, increasing at hourly intervals. Systemic reactions were classified according to the World Allergy Organization grade system.
Results: Systemic reactions occurred in 14 patients (73.7%). The mean time to adverse reactions after the last injection was 36 minutes, and the majority of systemic reactions were pruritus and urticaria. In addition, the injection of HDM alone or HDM plus pollen caused more than grade 2 systemic reactions in about 50% each of the patients.
Conclusion: Since ultra-RIT caused a higher incidence of systemic reactions in children and adolescents, it should be carried out cautiously in the hospitalization rather than the office.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Brozek JL / 2010 / Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision / J Allergy Clin Immunol 126 : 466 ~ 476
Calabria CW / 2013 / Accelerated immunotherapy schedules / Curr Allergy Asthma Rep 13 : 389 ~ 398
Calderon MA / 2012 / Multiple-allergen and single-allergen immunotherapy strategies in polysensitized patients: looking at the published evidence / J Allergy Clin Immunol 12
Castro-Rodriguez JA / 2000 / A clinical index to define risk of asthma in young children with recurrent wheezing / Am J Respir Crit Care Med 162 (4 Pt 1) : 1403 ~ 1406
Cox L / 2006 / Accelerated immunotherapy schedules: review of efficacy and safety / Ann Allergy Asthma Immunol 97 : 126 ~ 137
Calabria CW / 2013 / Accelerated immunotherapy schedules / Curr Allergy Asthma Rep 13 : 389 ~ 398
Calderon MA / 2012 / Multiple-allergen and single-allergen immunotherapy strategies in polysensitized patients: looking at the published evidence / J Allergy Clin Immunol 12
Castro-Rodriguez JA / 2000 / A clinical index to define risk of asthma in young children with recurrent wheezing / Am J Respir Crit Care Med 162 (4 Pt 1) : 1403 ~ 1406
Cox L / 2006 / Accelerated immunotherapy schedules: review of efficacy and safety / Ann Allergy Asthma Immunol 97 : 126 ~ 137
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