지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Serum or plasma is free of cellular components. As DNA is in the nucleus or mitochondria of a cell, it can be presumed that serum/plasma is DNA free.
However, there are cases wherein serum/plasma is the only resource available for identification analysis, yet no sufficient data are available regarding whether reliable DNA testing can be applied to such cases, and what the influencing factors are when testing is a valid course of action. The aim of this study is to illustrate the factors that can be used in the genetic testing of serum/plasma when identifying an individual. The results showed that the concentration of serum DNA significantly increased over time in 4°C storage, and the DNA yields from samples stored in heparin tubes were overall higher than from samples stored in ethylenediaminetetraacetic acid tubes. We observed that the concentration of DNA in serum successfully matched 100% to the short tandem repeat data of blood DNA.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Lo YM / 1998 / Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis / Am J Hum Genet 62:768~775
이지현 / 2013 / 혈청(serum)을 이용한 STR분석 사례보고 / 대한법의학회지 37(4):220~223
Takayama T / 2001 / Origin of DNA in human serum and usefulness of serum as a material for DNA typing / Leg Med (Tokyo) 3:109~113
Honda H / 2002 / Fetal gender determination in early pregnancy through qualitative and quantitative analysis of fetal DNA in maternal serum / Hum Genet 110:75~79
Bischoff FZ / 2002 / Cell-free fetal DNA and intact fetal cells in maternal blood circulation: implications for first and second trimester non-invasive prenatal diagnosis / Hum Reprod Update 8:493~500
이지현 / 2013 / 혈청(serum)을 이용한 STR분석 사례보고 / 대한법의학회지 37(4):220~223
Takayama T / 2001 / Origin of DNA in human serum and usefulness of serum as a material for DNA typing / Leg Med (Tokyo) 3:109~113
Honda H / 2002 / Fetal gender determination in early pregnancy through qualitative and quantitative analysis of fetal DNA in maternal serum / Hum Genet 110:75~79
Bischoff FZ / 2002 / Cell-free fetal DNA and intact fetal cells in maternal blood circulation: implications for first and second trimester non-invasive prenatal diagnosis / Hum Reprod Update 8:493~500
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