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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 447 - 451 (5page)
- DOI
- 10.15188/kjopp.2016.12.30.6.447
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In this study, Albizziae Cortex extracts (ACE) have potent effects on adipogenesis and on lipolysis in OP9 cells. There was no cytotoxicity while cells were treated with ACE in designated time intervals, unaffected by various concentrations. In the cells with ACE-treated, increases in fat storage were inhibited, and also confirmed by Oil red O. To understand the underlying mechanism at the molecular level, the effects of ACE were examined on the expression of the genes involved in adipogenesis by using real-time PCR. In this cell model, the mRNA level of adipogenic genes such as peroxisome-proliferator-activated receptors gamma (PPARγ) and CAAAT/enhancer binding protein alpha (C/EBPα) were decreased by ACE treatment, comparing with those of control group. Collectively, our data suggest that ACE may have great potential as a novel anti-obesity agent.
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서론
재료 및 방법
결과
고찰
결론
References
참고문헌 (18)
참고문헌 신청
[학술지(정기간행물)] - Otto, T. C. / 2005 / Adipose development from stem cell to adipocyte / Crit. Rev. Biochem. Mol. Biol. 40 : 229 ~ 242
[학술지(정기간행물)] - MacDougald, O. A. / 1995 / Transcriptonal regulation of gene expression during adipocyte differentiation / Annu. Rev. Biochem. 64 : 345 ~ 373
[학술지(정기간행물)] - Trujillo, M. E. / 2006 / Adipose tissue-derived factors: impact on health and disease / Endocr. Rev. 27 (7) : 762 ~ 778
[학술지(정기간행물)] - Gregoire, F. M. / 1998 / Understanding adipocyte differentiation / Physiol. Rev. 78 (3) : 783 ~ 809
[학술지(정기간행물)] - Heo, S. Y. / 1997 / Intervention and Discussion of Obesity in East-West Medicine / J. Of Oriental Rehabilitation Medicine 7 (1) : 272 ~ 286
[학술지(정기간행물)] - MacDougald, O. A. / 1995 / Transcriptonal regulation of gene expression during adipocyte differentiation / Annu. Rev. Biochem. 64 : 345 ~ 373
[학술지(정기간행물)] - Trujillo, M. E. / 2006 / Adipose tissue-derived factors: impact on health and disease / Endocr. Rev. 27 (7) : 762 ~ 778
[학술지(정기간행물)] - Gregoire, F. M. / 1998 / Understanding adipocyte differentiation / Physiol. Rev. 78 (3) : 783 ~ 809
[학술지(정기간행물)] - Heo, S. Y. / 1997 / Intervention and Discussion of Obesity in East-West Medicine / J. Of Oriental Rehabilitation Medicine 7 (1) : 272 ~ 286
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UCI(KEPA) : I410-ECN-0101-2017-519-001974846