Seropositivity of Toxoplasmosis in Pregnant Women by ELISA at Minia University Hospital, Egypt

Amany M. Kamal; Azza K. Ahmed; Manal Z. M. Abdellatif; Mohamed Tawfik; Ebtesam E. Hassan

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자료유형: 학술저널

저자정보: Amany M. Kamal (Minia University) Azza K. Ahmed (Minia University) Manal Z. M. Abdellatif (Minia University) Mohamed Tawfik (Minia University) Ebtesam E. Hassan (Minia University)

저널정보: 대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.53 No.5

발행연도: 2015.10

수록면: 605 - 610 (6page)

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Toxoplasmosis is considered as an important risk factor for bad obstetric history (BOH) and one of the major causes of congenitally acquired infections. The present study aimed to estimate the seropositivity of T. gondii infection and associated risk factors among the attendees of high risk pregnancy and low risk antenatal care clinic of Minia Maternity and Pediatric University Hospital, Minia, Egypt. The study was carried out from April 2013 to April 2014 through 2 phases, the first phase was case-control study, and the second phase was follow-up with intervention. A total of 120 high risk pregnant and 120 normal pregnant females were submitted to clinical examinations, serological screening for anti-Toxoplasma IgM and IgG antibodies by ELISA, and an interview questionnaire. Seropositive cases were subjected to spiramycin course treatment. The results showed that the seroprevalence of toxoplasmosis in high-risk pregnancy group was 50.8%, which was significantly different from that of normal pregnancy group (P<0.05). Analysis of seropositive women in relation to BOH showed that abortion was the commonest form of the pregnancy wastage (56.5%). The high prevalence of T. gondii seropositive cases was observed in the age group of 21-30 years. Post-delivery adverse outcome was observed in 80.3% of high-risk pregnancy group compared to 20% of normal pregnancy group. There was a statistically significant relationship between seropositivity and living in rural area, low socioeconomic level, and undercooked meat consumption (P<0.05). Serological screening for anti-Toxoplasma antibodies should be routine tests especially among high-risk pregnant women.

#Toxoplasma gondii #toxoplasmosis #high-risk pregnancy #neonatal outcome #seropositivity #ELISA

참고문헌 (29)

참고문헌 신청

[단행본] - Dubey JP / 2010 / Toxoplasmosis of Animals and Humans / CRC Press

[학술지(정기간행물)] - Torgerson PR / 2013 / Global burden of congenital toxoplasmosis: systematic review / Bull World Health Organ 91 : 501 ~ 508

[학술지(정기간행물)] - Fricker-Hidalgo H / 2013 / Toxoplasma seroconversion with negative or transient immunoglobulin M in pregnant women: myth or reality? A French multicenter retrospective study / J Clin Microbiol 51 : 2103 ~ 2111

[학술지(정기간행물)] - Sarkar MD / 2012 / Seropositivity of toxoplasmosis in antenatal women with bad obstetric history in a tertiary-care hospital of Andhra Pradesh, India / J Health Popul Nutr 30 : 87 ~ 92

[학술지(정기간행물)] - Kumari N / 2011 / Is screening of TORCH worthwhile in women with bad obstetric history: an observation from eastern Nepal / J Health Popul Nutr 29 : 77 ~ 80

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