지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.6
- 수록면
- 67 - 78 (12page)
이용수
초록· 키워드
오류제보하기
Glycopeptides of the clinically important antibiotic drugs are glycosylated cyclic or polycyclic nonribosomal peptides. Glycopeptides such as vancomycin and teicoplanin are often used for the treatment of gram-positive bacteria in patients. The increased incidence of drug resistance and inadequacy of these therapeutics against gram-positive bacterial infections would be the formation and clinical development of more variable second generation of glycopeptide antibiotics: semisynthetic lipoglycopeptide analogs such as telavancin, dalbavancin, and oritavancin with improved activity and better pharmacokinetic properties. In this review, we describe the development of and bacterial resistance to vancomycin, teicoplanin, and semisynthetic glycopeptides (teicoplanin, dalbavancin, and oritavancin). The clinical influence of resistance to glycopeptides, particularly vancomycin, are also discussed.
목차
INTRODUCTION
CHEMICAL STRUCTURE OF NATURAL GLYCOPEPTIDES
SEMISYNTHETIC GLYCOPEPTIDES
THE MECHANISM OF ACTION
MECHANISMS OF BACTERIAL RESISTANCE
CONCLUSION
REFERENCES
참고문헌 (59)
참고문헌 신청
[학술지(정기간행물)] - James RC / 2012 / Redesign of glycopeptide antibiotics: back to the future / ACS Chem Biol 7 : 797 ~ 804
[학술지(정기간행물)] - Butler MS / 2014 / Glycopeptide antibiotics: back to the future / J Antibiot (Tokyo) 67 : 631 ~ 644
[학술지(정기간행물)] - Reynolds PE / 1989 / Structure, biochemistry and mechanism of action of glycopeptide antibiotics / Eur J Clin Microbiol Infect Dis 8 : 943 ~ 950
[학술지(정기간행물)] - Binda E / 2014 / Old and New glycopeptide antibiotics: action and resistance / Antibiotics 3 : 572 ~ 594
[학술지(정기간행물)] - Marcone GL / 2014 / Relationship between glycopeptide production and resistance in the actinomycete Nonomuraea sp. ATCC 39727 / Antimicrob Agents Chemother 58 : 5191 ~ 5201
[학술지(정기간행물)] - Butler MS / 2014 / Glycopeptide antibiotics: back to the future / J Antibiot (Tokyo) 67 : 631 ~ 644
[학술지(정기간행물)] - Reynolds PE / 1989 / Structure, biochemistry and mechanism of action of glycopeptide antibiotics / Eur J Clin Microbiol Infect Dis 8 : 943 ~ 950
[학술지(정기간행물)] - Binda E / 2014 / Old and New glycopeptide antibiotics: action and resistance / Antibiotics 3 : 572 ~ 594
[학술지(정기간행물)] - Marcone GL / 2014 / Relationship between glycopeptide production and resistance in the actinomycete Nonomuraea sp. ATCC 39727 / Antimicrob Agents Chemother 58 : 5191 ~ 5201
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