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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 129 - 134 (6page)
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Purpose: Enterococci are a common cause of urinary tract infection and vancomycin-resistant strains are more difficult to treat. The purpose of this surveillance program was to assess the prevalence of and determine the risk factors for vancomycin resistance in adults among urinary isolates of Enterococcus sp. and to detail the antibiotic susceptibility profile, which can be used to guide empirical treatment. Materials and Methods: From 2005 to 2014 we retrospectively reviewed 5,528 positive Enterococcus sp. urine cultures recorded in a computerized laboratory results database at a tertiary teaching hospital in Cambridge, United Kingdom. Results: Of these cultures, 542 (9.8%) were vancomycin resistant. No longitudinal trend was observed in the proportion of vancomycin-resistant strains over the course of the study. We observed emerging resistance to nitrofurantoin with rates climbing from near zero to 40%. Ampicillin resistance fluctuated between 50% and 90%. Low resistance was observed for linezolid and quinupristin/dalfopristin. Female sex and inpatient status were identified as risk factors for vancomycin resistance. Conclusions: The incidence of vancomycin resistance among urinary isolates was stable over the last decade. Although resistance to nitrofurantoin has increased, it still serves as an appropriate first choice in uncomplicated urinary tract infection caused by vancomycin-resistant Enterococcus sp.
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참고문헌 (21)
참고문헌 신청
Heintz BH / 2013 / Evaluation of the treatment of vancomycin-resistant enterococcal urinary tract infections in a large academic medical center / Ann Pharmacother 47:159~169
Heintz BH / 2010 / Vancomycin-resistant enterococcal urinary tract infections / Pharmacotherapy 30:1136~1149
Lloyd-Smith P / 2013 / Economic analysis of vancomycin-resistant enterococci at a Canadian hospital: assessing attributable cost and length of stay / J Hosp Infect 85:54~59
Werner G / 2008 / Emergence and spread of vancomycin resistance among enterococci in Europe / Euro Surveill 13(47)
Center for Disease Control and Prevention / Information for the public about VRE. 2008
Heintz BH / 2010 / Vancomycin-resistant enterococcal urinary tract infections / Pharmacotherapy 30:1136~1149
Lloyd-Smith P / 2013 / Economic analysis of vancomycin-resistant enterococci at a Canadian hospital: assessing attributable cost and length of stay / J Hosp Infect 85:54~59
Werner G / 2008 / Emergence and spread of vancomycin resistance among enterococci in Europe / Euro Surveill 13(47)
Center for Disease Control and Prevention / Information for the public about VRE. 2008
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