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학술저널
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대한바이러스학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY 大韓바이러스學會誌 제17권 제2호
발행연도
1987.12
수록면
99 - 105 (7page)

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Korean hemorrhagic fever was known to the world for the first time during the Korean War and its causative agent, Hantaan virus was discovered by Lee and Lee in 1976. Following this discovery, it became apparent that similar diseases such as Hemorrhagic nephrosonephritis in the Soviet Union, Nephropathia epidemica in Scandinavia, Epidemic hemorrhagic fever in China and Japan and Epidemic nephritis in Eastern Europe are caused by Hantaan and related viruses. Therefore in 1982, WHO recornmanded that the above mentioned diseases with different names should be refered to as Haemorrhagic fever with renal syndrome (HFRS). Recent seroepidemiologic surveys show that closely related agents antigenically similar to Hantaan virus are widely distributed in the world to a much greater geographic extent than previously recognized. This study was to prove the existence of Hantaan or related virus infection among the residents and the rats in the Hawaiian islands that is located in the center of the Pacific Ocean and the results are surnmarized as follows: 1. Rattus rattus, Rattus norvegicus, and Rattus exulans had antibodies against Hantaan yirus in the proportion of 84 to 1,159 (7.2%), 30 to 169 (17%), and 12 to 202 (5.9%) respectively. 2. Among 216 healthy Hawaiians, 4 persons had antibodies (1.9%). However, prevalence of antibody to Hantaan virus among Vector Control Personnel worked in Hawaii State Department of Health was 30.6% (11/36). 3. Hantaan virus antigen was not demonstrable in the lung tissues of antibody positive rats. 4. Up to the present tirne, there was no patient ever diagnosed as Haemorrhagic fever with renal syndrome clinically in the Hawaiian islands. The results of this study indicate that Hantaan virus or similar virus exists in the Hawaiian islands and further study is needed to demonstrate the occurrence of HFRS patient and to isolate Hantavirus in this area.

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