지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.4
- 수록면
- 263 - 275 (13page)
이용수
초록· 키워드
오류제보하기
Impaired fasting glucose (IFG) is one of significant risk factors of developing diabetes. The persons with IFG are, thus, an important target group for primary prevention of diabetes. It is well known that plasma homocysteine concentration may be increased in poor folate nutritional status. Elevated level of plasma homocysteine is considered as a marker of enhanced oxidative stress. In addition, the protective effect against oxidative stress may be diminished in poor antioxidative nutrient status as vitamin C. It is, therefore, important to maintain adequate nutritional status of folate and vitamin C in the patients with type 2 diabetes or IFG. This study was performed to determine the effects of supplementation of folic acid or vitamin C on plasma concentrations of homocysteine, oxidized LDL, and lipids and on the activity of plasma anti-oxidative enzyme in patients with IFG. A total of 97 patients with IFG were participated voluntarily with written consents. They were divided into one of the four experimental groups; Control (C), Folatesupplemented (F), Ascorbate-supplemented (A), and Folate plus ascorbate-supplemented (FA). The subjects in C were taken placebo, those in F were supplemented 1 mg of folate, those in A were received 1,000 mg of vitamin C, and those in FA were given 1 mg of folate plus 1,000 mg of vitamin C daily for 4 weeks. No change in plasma concentrations of vitamin C, lipids, and oxidized LDL and the activity of GSH-Px were observed in vitamin C-supplemented group (A+FA) and folate-supplemented group (F+FA) compared to the placebo group (C+A). Only the folate-supplemented group (F+FA) had significantly increased average serum folate concentration and lowered plasma homocysteine concentration compared to the placebo group (C+A). Thus, it should be recommended the patients with IFG to increase folate intake through diets and, if it is not sufficient, to take folic acid supplements to prevent the development of complications induced by hyperhomocysteinemia as well as oxidative stress. (Korean J Community Nutrition 13(2):263~275, 2008)
목차
등록된 정보가 없습니다.
참고문헌 (67)
참고문헌 신청
1. [학술지(정기간행물)] - Al-Obaidi MK / 2000 / Elevated homocysteine levels are associated with increased ischemic myocardial injury in acute coronary syndromes / J Am Coll Cardiol 36 (4) : 1217 ~ 1222
2. [학술지(정기간행물)] - Asayama K / 1994 / Serum antioxidant states in streptozotocininduced diabetic rat / Horm metab Res 26 (7) : 313 ~ 315
3. [학술지(정기간행물)] - Aukrus P / 1997 / Elevated plasma levels of reduced homocysteine in common variable immunodeficiency-a marker of enhanced oxidative stress / Eur J Clin Invest 27 (10) : 723 ~ 730
4. [단행본] - Bennett PH / 1990 / Epidemiology of diabetes mellitus. In Diabetes Mellitus Theory and Practice / Elsevier : 357 ~ 377
5. [학술지(정기간행물)] - Blom HJ / 1995 / Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinemia / Eur J Clin Invest 25 (3) : 149 ~ 154
2. [학술지(정기간행물)] - Asayama K / 1994 / Serum antioxidant states in streptozotocininduced diabetic rat / Horm metab Res 26 (7) : 313 ~ 315
3. [학술지(정기간행물)] - Aukrus P / 1997 / Elevated plasma levels of reduced homocysteine in common variable immunodeficiency-a marker of enhanced oxidative stress / Eur J Clin Invest 27 (10) : 723 ~ 730
4. [단행본] - Bennett PH / 1990 / Epidemiology of diabetes mellitus. In Diabetes Mellitus Theory and Practice / Elsevier : 357 ~ 377
5. [학술지(정기간행물)] - Blom HJ / 1995 / Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinemia / Eur J Clin Invest 25 (3) : 149 ~ 154
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
제2형 당뇨병 환자에게 엽산과 아스코르브산 보충이 혈장 호모시스테인 농도와 산화 스트레스에 미치는 영향
한국영양학회지
2009 .03
-
관상동맥협착 환자의 혈장 총 Homocysteine, 엽산 및 비타민 B₁₂ 농도
대한지역사회영양학회지
2005 .12
-
Effects of folic acid supplementation on serum homocysteine levels, lipid profiles, and vascular parameters in post-menopausal Korean women with type 2 diabetes mellitus
Nutrition Research and Practice
2017 .08
-
Effects of folic acid supplementation on serum homocysteine levels, lipid profiles, and vascular parameters in post-menopausal Korean women with type 2 diabetes mellitus
Nutrition Research and Practice
2017 .08
-
Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B₁₂-deficient rats
Nutrition Research and Practice
2009 .06
-
Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B₁₂-deficient rats
Nutrition Research and Practice
2009 .06
-
불임여성에서 엽산 보충이 혈증 호모시스테인과 비타민 B 수준에 미치는 영향
한국영양학회지
2005 .04
-
울산지역 당뇨 질환 노인의 항산화 영양소 섭취실태 및 혈액 항산화 영양상태
대한지역사회영양학회지
2008 .04
-
일부여대생의 혈장 호모시스테인 함량과 비타민 B₆, B₁₂ 및 엽산 영양상태
한국영양학회지
2002 .01
-
지구력 훈련이 혈중 호모시스테인과 비타민 B 수준에 미치는 영향 : 남자 고등학생 필드하키선수를 대상으로
한국영양학회지
2004 .12
-
한국 성인 남녀의 엽산 영양상태와 혈장 호모시스테인 농도
한국영양학회지
2001 .06
-
Plasma Concentrations of Vitamins E and A, and Effects of Vitamin E Supplementation on Oxidative Stress and Immune Status in Korean Non-Insulin Dependent Diabetic Patients
Nutritional Sciences
1998 .11
-
중년기의 비타민ㆍ무기질 보충제 사용량과 건강관련 생활습관 조사
대한지역사회영양학회지
2004 .06
-
Disturbed homocysteine metabolism is associated with cancer
Experimental and Molecular Medicine
2019 .01
-
Effects of Antioxidant Supplementation on Antioxidant Status and PHA-Stimulated Interleukin-2 Production by Peripheral Blood Mononuclear Cells in the Elderly Women
Journal of Community Nutrition
2005 .03
-
불임 여성의 비타민 B 영양 상태 및 혈청 호모시스테인 수준
한국영양학회지
2004 .03
-
Evaluation of vitamin B6 intake and status of 20- to 64-year-old Koreans
Nutrition Research and Practice
2014 .12
-
Evaluation of vitamin B6 intake and status of 20- to 64-year-old Koreans
Nutrition Research and Practice
2014 .12
-
지질의 종류를 달리하였을때 식이내 Vitamin E첨가가 흰쥐의 혈청 Vitamin E농도 및 지질성분에 미치는 영향
한국영양학회지
1987 .02
-
Homocysteine and Total Antioxidant Status in Acute Myocardial Infarction Patients Among Tamil Population
Integrative biosciences
2007 .01
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Effect of intravenous ascorbic acid administration on fatigue after laparoscopic myomectomy: A randomized, double-blind, placebo-controlled trial
Woo Yeon Hwang
,
Kidong Kim
한국산학기술학회 논문지
2021
.02
The effects of ascorbic acid on the morphology and cell proliferation of three-dimensional stem cell spheroids
Hyunjin Lee
,
Seong-Il Yeo
,
Jun-Beom Pa
외 1명
대한치과의사협회지
2017
.09
제2형 당뇨병 환자에게 엽산과 아스코르브산 보충이 혈장 호모시스테인 농도와 산화 스트레스에 미치는 영향
황미리
,
소주련
,
임현숙
한국영양학회지
2009
.03
비만 남자 대학생의 혈청 지질, 인슐린 및 혈장 아스코르브산의 농도에 관한 연구
구진영
,
김경업
,
박미영
외 2명
동아시아식생활학회지
2010
.08
최근 본 자료
댓글(0)
0