개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2005.3
- 수록면
- 42 - 48 (7page)
이용수
초록· 키워드
오류제보하기
This study was done to investigate effects of antioxidant supplementation on phytohemagglutinin(PHA)-stimulated interleukin-2(IL-2) production by peripheral blood mononuclear cells(PBMCs) in elderly women. This study was designed as a placebo-controlled, single-blinded, randomized intervention trial. Twenty four elderly women aged over 60years, visitings social welfare center in Seoul were divided into 3 groups, placebo(n = 8), vitamin C supplemented (n = 8), and vitamin E supplemented(n = 8) groups. Experimental groups were given either 1000mg of L-ascorbic acid or 400 IU of d-α-tocopherol for 4 weeks. There was no significant difference in antioxidant vitamins intakes and their plasma levels among pre-intervention groups. Plasma viatmin C or E levels was significantly increased after vitamin C or E supplementations. The increases of plasma thiobarbituric acid-reactive substance(TBARS) levels in the placebo group were significantly higher than those of the supplemented 2 groups. There were no significant differences in the changes of plasma IL-2 level between pre- and post-intervention among the 3 groups. However there was a significant increase in PHAstimulated IL-2 production by PBMCs after 4-week vitamin E or vitamin C supplementation. Particularly, vitamin E supplemented group showed a higher PHA-stimulated IL-2 production than vitamin C supplemented group. These results indicate that vitamin E or vitamin C supplementation might enhance mitogen-stimulated cytokine production by immune cells, which could be one of the factors to improve health status in the elderly.
목차
ABSTRACT
Introduction
Subjects and Methods
Results
Discussion
References
참고문헌 (30)
참고문헌 신청
[학술지(정기간행물)] - Adolfson O / 2001 / Vitamin E-enhanced IL-2 production in old mice Naive but not memory T cells show increased cel division cycling and IL-2-producing capacity 167 (l 167) : 3809 ~ 3817
[학술지(정기간행물)] - Bergsten P / 1990 / Millimolar concentration of ascorbic acid in purified human mononuclear leukocytes : 2584 ~ 2587
[학술지(정기간행물)] - Bieri JG / 1985 / Determination of indivi-dual carotenoid in human plasma by high performance liquid chromatography : 474 ~ 484
[학술지(정기간행물)] - Bieri JG / 1979 / Simultaneous determi-nation of alpha-tocopherol and retinol in plasma or red blood cels by high pressure liquid chromatography : 2143 ~ 2149
[학술지(정기간행물)] - Cakman I / 1996197-209 / Dysregulation between TH1 and TH2 T cell subpopulations in the elderly 87 : 197 ~ 209
[학술지(정기간행물)] - Bergsten P / 1990 / Millimolar concentration of ascorbic acid in purified human mononuclear leukocytes : 2584 ~ 2587
[학술지(정기간행물)] - Bieri JG / 1985 / Determination of indivi-dual carotenoid in human plasma by high performance liquid chromatography : 474 ~ 484
[학술지(정기간행물)] - Bieri JG / 1979 / Simultaneous determi-nation of alpha-tocopherol and retinol in plasma or red blood cels by high pressure liquid chromatography : 2143 ~ 2149
[학술지(정기간행물)] - Cakman I / 1996197-209 / Dysregulation between TH1 and TH2 T cell subpopulations in the elderly 87 : 197 ~ 209
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Antioxidant Status and its Relationship to Plasma Cytokine Levels in Korean Elderly Women Living in Seoul
Journal of Community Nutrition
2004 .09
-
울산지역 당뇨 질환 노인의 항산화 영양소 섭취실태 및 혈액 항산화 영양상태
대한지역사회영양학회지
2008 .04
-
Vitamin A supplementation modifies the antioxidant system in rats
Nutrition Research and Practice
2016 .02
-
Vitamin A supplementation modifies the antioxidant system in rats
Nutrition Research and Practice
2016 .02
-
여자노인에서 항산화 비타민 보충이 혈장 지질 개선에 미치는 영향
대한지역사회영양학회지
2006 .02
-
젊은 여성의 계절별 옥외활동시간과 혈청 25-(OH) 비타민 D 영양상태
대한지역사회영양학회지
2014 .06
-
Dietary source of vitamin B₁₂ intake and vitamin B₁₂ status in female elderly Koreans aged 85 and older living in rural area
Nutrition Research and Practice
2010 .06
-
Dietary source of vitamin B₁₂ intake and vitamin B₁₂ status in female elderly Koreans aged 85 and older living in rural area
Nutrition Research and Practice
2010 .06
-
Nutritional Status of Antioxidant Vitamins in the Elderly Living in Ulsan Metropolitan City
Journal of Community Nutrition
2001 .11
-
Evaluation of vitamin B6 intake and status of 20- to 64-year-old Koreans
Nutrition Research and Practice
2014 .12
-
Evaluation of vitamin B6 intake and status of 20- to 64-year-old Koreans
Nutrition Research and Practice
2014 .12
-
중년기의 비타민ㆍ무기질 보충제 사용량과 건강관련 생활습관 조사
대한지역사회영양학회지
2004 .06
-
지질의 종류를 달리하였을때 식이내 Vitamin E첨가가 흰쥐의 혈청 Vitamin E농도 및 지질성분에 미치는 영향
한국영양학회지
1987 .02
-
비타민 E 보충이 여자 운동선수들의 항산화능과 면역능력에 미치는 영향
한국영양학회지
1999 .10
-
Estimation of vitamin K intake in Koreans and determination of the primary vitamin K-containing food sources based on the fifth Korean National Health and Nutrition Examination Survey (2010-2011)
Nutrition Research and Practice
2013 .12
-
Estimation of vitamin K intake in Koreans and determination of the primary vitamin K-containing food sources based on the fifth Korean National Health and Nutrition Examination Survey (2010-2011)
Nutrition Research and Practice
2013 .12
-
Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B₁₂-deficient rats
Nutrition Research and Practice
2009 .06
-
Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B₁₂-deficient rats
Nutrition Research and Practice
2009 .06
-
항산화성 비타민 보충 급여가 흡연자의 혈액성상에 미치는 영향
한국영양학회지
1998 .04
-
항산화성 비타민 보충 급여가 흡연자의 혈중 지질 양상에 미치는 영향
한국영양학회지
1998 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0