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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.3 No.3
발행연도
1998.9
수록면
282 - 286 (5page)

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To determine the immune effect of kimchi extracts in mice, 0.5 ㎎/day of the extracts from kimchis, which were prepared with conventionally (general kimchi) and organically (organic kimchi) cultivated ingredients, were treated orally to male BALB/c mice. Following 1, 3 and 5 weeks of treatment, the Interleukin-2 (IL-2) production in the presence (con A-stimulated) or the absence (spontaneous) of con A (5㎍/ml) and the natural killer cell (NK) activity of the splenocytes were measured. The IL-2 productions in most of treatments with methanol extract from general kimchi were significantly higher than those of control (p<0.05). And at the 3 weeks of treatment, the spontaneous or con A-stimulated IL-2 productions from splenocytes of mice treated with it increased more than those of control group, by 2.8 and 2.2 times, respectively. However, the longer the treatment with methanol extracts from organic kimchi showed the higher the enhancing effect on the IL-2 production. The spontaneous or con A-stimulated IL-2 productions from splenocytes of mice treated with dichloromethane fraction from general kimchi also increased at 5 weeks of teatment compared to those of control group, by 2.7 and 2.5 times, respectively. The natural killer cell activity of splenocytes from mice treated with methanol extracts from general kimchi for 1~5 weeks was significantly higher than that of control goup (p<0.01). The effect of methanol extracts from general kimchi was the highest at 3 weeks of treatment, as same as in the IL-2 production. The enhancing effect of methanol extracts from organic kimchi on the NK cell activity was the highest at 5 weeks of treatment. The NK cell activity of splenocytes from mice treated with dichloromethane fraction from general kimchi for 5 weeks was significantly higher than those in control and 3 weeks of treatment. These results showed that the effects of kimchi extracts on the IL-2 production and the NK cell activity in mice were profound in long term of treatment (3 and 5 weeks than 1 week). We suggest that kimchi extracts might have an immune effect in part due to its enhancing action on the IL-2 production and the NK cell activity.

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Abstract

INTRODUCTION

MATERIALS AND METHODS

RESULTS AND DISCUSSION

ACKNOWLEDGEMENTS

REFERENCES

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