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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국진공학회(ASCT) Applied Science and Convergence Technology Applied Science and Convergence Technology Vol.33 No.5
- 발행연도
- 2024.9
- 수록면
- 117 - 125 (9page)
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초록· 키워드
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Point-of-care testing (POCT) equipment has transformed healthcare management by allowing rapid and accurate diagnostics at the point of care. It enables immediate clinical decisions to be taken, leading to improved outcomes. This review highlights the advances in the field of POCT achieved by integrating molecular diagnostics with advanced bioengineering techniques in the development of POCT devices. At present, POCT devices span simple glucose meters to sophisticated handheld devices for monitoring chronic diseases and detecting infectious diseases. Traditional polymerase chain reaction (PCR) has been significantly enhanced in sensitivity and specificity in terms of POCT by the innovation of the photonic PCR and digital PCR, which gives results in minutes with improved diagnostic accuracy. Clustered regularly interspaced short palindromic repeats-based graphene field-effect transistor and bioelectronic devices developed through bio-microelectromechanical system technology meanwhile have further revolutionized rapid and precise diagnostics. Additionally, lateral flow assays (LFAs) are versatile instruments essential for addressing global health challenges in managing infectious disease outbreaks. LFAs are also suitable for resource-limited countries. This review sheds light on scientific principles, technological progress, and practical applications of POCT.
목차
ABSTRACT
1. Introduction
2. PCR
3. Bioelectronic devices
4. LFAs
5. Future directions and conclusion
References
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