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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2025.2
- 수록면
- 86 - 97 (12page)
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초록· 키워드
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The burgeoning field of immunometabolism highlights the interdependence between metabolic programs and efficacious immune responses. The current understanding that cellular metabolic remodeling is necessary for a competent adaptive immune response, along with acutely sensitive methodologies such as high-performance liquid chromatography/mass spectrometry and advanced proteomics, have ushered in a renaissance of lipid- and metabolic-based scientific inquiries. One facet of recent interest examines how lipids function as post-translational modifications (PTMs) and their resulting effects on adaptive immune responses. The goal of this review is to establish a fundamental understanding of these protein modifications and highlight recent findings that underscore the importance of continued investigation into lipids as PTMs.
목차
ABSTRACT
DE NOVO CHOLESTEROL AND FATTY ACID SYNTHESIS AND ADAPTIVE IMMUNE OUTCOMES
LIPIDS AS PTMs
PRENYLATION
N-MYRISTOYLATION
S-ACYLATION (PALMITOYLATION)
CONCLUDING REMARKS
REFERENCES
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