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논문 기본 정보

자료유형
학술저널
저자정보
Nam Hyo-Kyoung (Department of Pediatrics, Korea University College of Medicine, Seoul, Korea) Lea Winnah Wu-In (Department of Radiology, Korea University College of Medicine, Seoul, Korea) Yang Zepa (Smart Health Care Center, Korea University Guro Hospital, Seoul, Korea; Korea University Guro Hospital-Medical Image Data Center (KUGH-MIDC), Seoul, Korea) Noh Eunjin (Smart Health Care Center, Korea University Guro Hospital, Seoul, Korea) Rhie Young-Jun (Department of Pediatrics, Korea University College of Medicine, Seoul, Korea) Lee Kee-Hyoung (Department of Pediatrics, Korea University College of Medicine, Seoul, Korea.) Hong Suk-Joo (Department of Radiology, Korea University College of Medicine, Seoul, Korea; Korea University Guro Hospital-Medical Image Data Center (KUGH-MIDC), Seoul, Korea)
저널정보
대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatric Endocrinology & Metabolism Vol.29 No.2
발행연도
2024.4
수록면
102 - 108 (7page)
DOI
10.6065/apem.2346050.025

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초록· 키워드

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Purpose: Bone age (BA) is needed to assess developmental status and growth disorders. We evaluated the clinical performance of a deep-learning-based BA software to estimate the chronological age (CA) of healthy Korean children.Methods: This retrospective study included 371 healthy children (217 boys, 154 girls), aged between 4 and 17 years, who visited the Department of Pediatrics for health check-ups between January 2017 and December 2018. A total of 553 left-hand radiographs from 371 healthy Korean children were evaluated using a commercial deep-learning-based BA software (BoneAge, Vuno, Seoul, Korea). The clinical performance of the deep learning (DL) software was determined using the concordance rate and Bland-Altman analysis via comparison with the CA.Results: A 2-sample <i>t</i>-test (<i>P</i><0.001) and Fisher exact test (<i>P</i>=0.011) showed a significant difference between the normal CA and the BA estimated by the DL software. There was good correlation between the 2 variables (<i>r</i>=0.96, <i>P</i><0.001); however, the root mean square error was 15.4 months. With a 12-month cutoff, the concordance rate was 58.8%. The Bland-Altman plot showed that the DL software tended to underestimate the BA compared with the CA, especially in children under the age of 8.3 years.Conclusion: The DL-based BA software showed a low concordance rate and a tendency to underestimate the BA in healthy Korean children.

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