지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.4
- 수록면
- 105 - 116 (12page)
이용수
초록· 키워드
오류제보하기
Acute necrotizing encephalopathy (ANE) is a rare but deadly complication with an unclear pathogenesis. We aimed to elucidate the immune characteristics of H1N1 influenza virus-associated ANE (IANE) and provide a potential therapeutic approach for IANE. Seven pediatric cases from a concentrated outbreak of H1N1 influenza were included in this study. The patients’ CD4+ T cells from peripheral blood decreased sharply in number but highly expressed Eomesodermin (Eomes), CD69 and PD-1, companied with extremely high levels of IL-6, IL-8 in the cerebrospinal fluid and plasma. Patient 2, who showed high fever and seizures and was admitted to the hospital very early in the disease course, received intravenous tocilizumab and subsequently showed a reduction in temperature and a stable conscious state 24 h later. In conclusion, a proinflammatory cytokine storm associated with activated CD4+ T cells may cause severe brain pathology in IANE. Tocilizumab may be helpful in treating IANE.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Influenza Virus-Derived CD8 T Cell Epitopes: Implications for the Development of Universal Influenza Vaccines
Immune Network
2024 .06
-
Estimating Influenza-associated Mortality in Korea: The 2009-2016 Seasons
예방의학회지
2019 .01
-
The 2009 H1N1 Pandemic Influenza in Korea
Tuberculosis and Respiratory Diseases
2016 .01
-
The Impact of Social Distancing on the Transmission of Influenza Virus, South Korea, 2020
Osong Public Health and Research Persptectives
2020 .01
-
Incidence, Severity, and Mortality of Influenza During 2010–2020 in Korea: A Nationwide Study Based on the Population-Based National Health Insurance Service Database
Journal of Korean Medical Science
2023 .02
-
Extrinsic Acquisition of CD80 by Antigen-Specific CD8⁺ T Cells Regulates Their Recall Immune Responses to Acute Viral Infection
Immune Network
2019 .08
-
Interim Estimates of 2023–2024 Seasonal Influenza Vaccine Effectiveness Among Adults in Korea
Journal of Korean Medical Science
2024 .04
-
Comparative Evaluation of the STANDARD F Influenza A/B FIA Test with the Sofia Influenza A+B FIA and SD BIOLINE Influenza Ag A/B/A(H1N1) tests for Influenza A Virus Detection
Annals of Clinical Microbiology
2021 .01
-
인플루엔자 감염으로 유발된 경련의 임상적 특징
대한소아신경학회지
2015 .09
-
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer
Immune Network
2023 .10
-
CD5 Expression Dynamically Changes During the Differentiation of Human CD8+ T Cells Predicting Clinical Response to Immunotherapy
Immune Network
2023 .08
-
Neonatal influenza virus infection affects myelination in influenza-recovered mouse brain
Journal of Veterinary Science
2018 .11
-
Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues
Immune Network
2016 .04
-
Modeling and Sequence Analysis of 2009 Influenza A(H1N1) Virus Mutant in Mice
한국실험동물학회 학술발표대회 논문집
2015 .08
-
All-Cause and Cause-Specific Mortality Attributable to Seasonal Influenza: A Nationwide Matched Cohort Study
Journal of Korean Medical Science
2023 .06
-
인플루엔자
대한내과학회지
2017 .01
-
The Korean Influenza National Immunization Program: History and Present Status
Infection and Chemotherapy
2017 .01
-
A Case of Influenza Associated Fulminant Myocarditis Successfully Treated with Intravenous Peramivir
Infection and Chemotherapy
2015 .01
-
Pathogenic Analysis of Mouse-Adapted 2009 Influenza A (H1N1) Mutant Virus
한국실험동물학회 학술발표대회 논문집
2015 .08
-
Social Distancing against COVID-19: Implication for the Control of Influenza
Journal of Korean Medical Science
2020 .01
이 논문과 함께 이용한 논문
Metabolic Signaling as a Driver of T Cell Aging
Minju Choi
,
Sujin Choi
,
Minkyeong Cho
외 1명
Immune Network
2025
.02
Oxidized LDL Accelerates Cartilage Destruction and Inflammatory Chondrocyte Death in Osteoarthritis by Disrupting the TFEB-Regulated Autophagy-Lysosome Pathway
Jeong Su Lee
,
Yun Hwan Kim
,
JooYeon Jhun
외 9명
Immune Network
2024
.06
Low-Dose Radiotherapy Attenuates Experimental Autoimmune Arthritis by Inducing Apoptosis of Lymphocytes and Fibroblast-Like Synoviocytes
Bo-Gyu Kim
,
Hoon Sik Choi
,
Yong-ho Choe
외 7명
Immune Network
2024
.08
Germinal Center Response to mRNA Vaccination and Impact of Immunological Imprinting on Subsequent Vaccination
Wooseob Kim
Immune Network
2024
.08
미토콘드리아 기능 이상과 암
한유선
,
제갈명은
,
김영진
생명과학회지
2019
.09
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-151-25-02-091069312