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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.8
- 수록면
- 421 - 429 (9page)
- DOI
- 10.9721/KJFST.2024.56.4.421
이용수
초록· 키워드
오류제보하기
Glycyrrhiza uralensis (licorice) has long been used for medicinal and dietary purposes. This study investigated the impact of fermented G. uralensis extract (FGE) and non-fermented G. uralensis extract (GE) on their antioxidant, anti-wrinkle, and anti-inflammatory effects. The results demonstrated that FGE exhibited increased polyphenol content and enhanced antioxidant capacities compared with GE. FGE also showed increased antioxidant enzyme activity, reinforcing cellular protection against oxidative stress in 3-morpholinosydnonimine-treated HaCaT cells. FGE also indicated elevated in vitro collagenase and elastase inhibitory effects compared with GE. Furthermore, FGE demonstrated excellent anti-inflammatory effects by suppressing inflammatory mediators such as nitric oxide, prostaglandin E₂, and interleukin-6 in lipopolysaccharide-treated RAW264.7 cells, indicating its potential in alleviating inflammatory conditions. Moreover, FGE decreased the levels of tumor necrosis factor-α and interleukin-6 cytokines compared with GE in phorbol 12-myristate 13- acetate plus A23187-stimulated HMC-1.2 cells. This study provides evidence that fermentation of G. uralensis enhances its antioxidant, anti-wrinkle, and anti-inflammatory effects.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Summary
References
참고문헌 (51)
참고문헌 신청
Abbas M, Saeed F, Anjum FM, Afzaal M, Tufail T, Bashir MS, Ishtiaq A, Hussain S, Suleria HaR. Natural polyphenols: An overview. Int. J. Food Prop. 20: 1689-1699 (2017)
Arcusa R, Carrillo JÁ, Cerdá B, Durand T, Gil-Izquierdo Á, Medina S, Galano JM, Villaño Valencia D, Marhuenda J, Zafrilla P. Anti-inflammatory and antioxidant capacity of a fruit and vegetable-based nutraceutical measured by urinary oxylipin concentration in a healthy population: A randomized, double-blind, placebo-controlled clinical trial. Antioxidants 11: 1342 (2022)
Beyer W, Imlay J, Fridovich I. Superoxide dismutases. Prog. Nucleic Acid Res. Mol. Biol. 40: 221-253 (1991)
Blois MS. Antioxidant determinations by the use of a stable free radical. Nature 181: 1199-1200 (1958)
Chen H, Tian T, Miao H, Zhao Y-Y. Traditional uses, fermentation, phytochemistry and pharmacology of phellinus linteus: A review. Fitoterapia 113: 6-26 (2016)
Arcusa R, Carrillo JÁ, Cerdá B, Durand T, Gil-Izquierdo Á, Medina S, Galano JM, Villaño Valencia D, Marhuenda J, Zafrilla P. Anti-inflammatory and antioxidant capacity of a fruit and vegetable-based nutraceutical measured by urinary oxylipin concentration in a healthy population: A randomized, double-blind, placebo-controlled clinical trial. Antioxidants 11: 1342 (2022)
Beyer W, Imlay J, Fridovich I. Superoxide dismutases. Prog. Nucleic Acid Res. Mol. Biol. 40: 221-253 (1991)
Blois MS. Antioxidant determinations by the use of a stable free radical. Nature 181: 1199-1200 (1958)
Chen H, Tian T, Miao H, Zhao Y-Y. Traditional uses, fermentation, phytochemistry and pharmacology of phellinus linteus: A review. Fitoterapia 113: 6-26 (2016)
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