지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.3
- 수록면
- 135 - 142 (8page)
- DOI
- https://doi.org/10.5483/BMBRep.2023-0250
이용수
초록· 키워드
오류제보하기
DNA methylation is one of the most extensively studied epigeneticregulatory mechanisms, known to play crucial roles invarious organisms. It has been implicated in the regulation ofgene expression and chromatin changes, ranging from globalalterations during cell state transitions to locus-specific modifications.
5-hydroxymethylcytosine (5hmC) is produced by amajor oxidation, from 5-methylcytosine (5mC), catalyzed by theten-eleven translocation (TET) enzymes, and is gradually beingrecognized for its significant role in genome regulation. Withthe development of state-of-the-art experimental techniques, ithas become possible to detect and distinguish 5mC and 5hmCat base resolution. Various techniques have evolved, encompassingchemical and enzymatic approaches, as well as thirdgenerationsequencing techniques. These advancements havepaved the way for a thorough exploration of the role of 5hmCacross a diverse array of cell types, from embryonic stem cells(ESCs) to various differentiated cells. This review aims to comprehensivelyreport on recent techniques and discuss the emergingroles of 5hmC.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
TET family dioxygenases and DNA demethylation in stem cells and cancers
Experimental and Molecular Medicine
2017 .01
-
Utilizing Deep Learning Model to Identify DNA N4-Methylcytosine Sites
대한전자공학회 학술대회
2020 .08
-
DNA N4- methylcytosine sites prediction using Convolutional Neural Network
대한전자공학회 학술대회
2020 .08
-
A CNN and LSTM based model for modification prediction of RNA 5-Hydroxymethylcytosine
대한전자공학회 학술대회
2022 .04
-
Direct Electrochemical Measurement of 5-Methylcytosine and Cytosine Using Micro Carbon Electrodes
대한기계학회 춘추학술대회
2019 .11
-
DNA methylation: an epigenetic mark of cellular memory
Experimental and Molecular Medicine
2017 .01
-
4mCPred-Caps: Identification of DNA N4-methylcytosine sites using CapsuleNet
제어로봇시스템학회 국제학술대회 논문집
2022 .11
-
하이브리드 메모리 큐브 (HMC) 시스템의 고속 직렬 링크 (SerDes)를 위한 모델링 및 성능 분석
대한임베디드공학회논문지
2017 .08
-
Maintenance of genome integrity and active homologous recombination in embryonic stem cells
Experimental and Molecular Medicine
2020 .08
-
Identification of 4mC modification sites based on ElasticNet and Machine Learning
제어로봇시스템학회 국내학술대회 논문집
2022 .06
-
i4mC-NN: Identification of 4mC sites in Rosaceae Genome Using Neural Network Architecture With Multiple Encoding Schemes
제어로봇시스템학회 국제학술대회 논문집
2022 .11
-
Genome Editing for Advanced Cell Therapies
한국생물공학회 학술대회
2022 .09
-
Dissecting single-cell genomes through the clonal organoid technique
Experimental and Molecular Medicine
2021 .10
-
Effects of Tumor Microenvironmental Factors on DNA Methylation and Radiation Sensitivity in A549 Human Lung Adenocarcinoma
방사선방어학회지
2018 .01
-
Development of culture strategies for stem cell maintenance and differentiation through regulation of cell behaviors
한국생물공학회 학술대회
2016 .04
-
층류 반응기를 이용한 고수분탄(HMC) 점화 특성 연구
한국에너지기후변화학회 학술대회
2016 .11
-
Advances in the multimodal analysis of the 3D chromatin structure and gene regulation
Experimental and Molecular Medicine
2024 .04
-
Epigenetic regulation and chromatin remodeling in learning and memory
Experimental and Molecular Medicine
2017 .01
-
Confirmation of no Causal Relationship between Genome-wide DNA Methylation and Transcriptome Changes after Gamma Irradiation
방사선산업학회지
2017 .01
최근 본 자료
댓글(0)
0