지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.3
- 수록면
- 12 - 39 (28page)
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초록· 키워드
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Antimicrobial agents have been a crucial discovery in modern medicine and have revolutionized the treatment of infectious diseases. However, the rampant overuse and misuse of these agents have resulted in the emergence of antimicrobial resistance (AMR), a global public health crisis that could lead to millions of deaths and severe economic losses. The dramatic rise in the occurrence of AMR-related deaths marks the beginning of the “post-antibiotic era.” As experts continue to work on devising new strategies that circumvent the development of AMR, focusing on a deeper understanding of the molecular factors that contribute to the persistence and transmission of resistance is the key approach in designing new therapeutic targets. This paper explores the various strategies that bacteria employ to evade the effects of antibiotics and provides an overview of the challenges in treating multidrug-resistant bacteria, including carbapenem-resistant Acinetobacter, methicillin-resistant Staphylococcus aureus, extended-spectrum β-lactamase-producing Enterobacteriaceae, multidrug-resistant (MDR)-Pseudomonas aeruginosa, and MDR-Mycobacterium tuberculosis. Emerging strategies for addressing antibiotic resistance, such as nanomaterials-based antimicrobials and CRISPR-Cas9 technology are also elucidated.
목차
INTRODUCTION
ANTIBIOTIC RESISTANCE MECHANISMS
ANTIBIOTIC RESISTANCE IN THE CLINICAL FIELD
CHALLENGES AND ADVANCEMENTS IN TREATING CRITICAL MDR BACTERIA
EMERGING MOLECULAR STRATEGIES FOR COMBATING ANTIBIOTIC RESISTANCE
CONCLUSION
REFERENCES
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