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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.6
- 수록면
- 183 - 192 (10page)
- DOI
- 10.17495/easdl.2024.6.34.3.183
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초록· 키워드
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This study examined the influence of green tea powder supplemented diet on bone formation, bone resorption markers, and bone metabolism-related hormones in female rats fed high fat and cholesterol diets. Twenty-one Sprague-Dawley female rats
(3 weeks old) were divided into the Control, High-fat, and Green-tea groups. The experimental diets were provided for 6 weeks. The serum and urine concentrations of calcium and phosphorus were determined. Serum ALP and urinary DPD crosslinks value were measured to monitor bone formation and resorption. Parathyroid hormones related to bone metabolism were determined. In summary, the weight increase at the end of the 6-week experiment was significantly higher in the high fat diet groups than in the Control group, but it was not significantly different from that of the Green-tea group. On the other hand, the serum P and urinary P excretion levels were significantly higher in rats in the Green-tea group than in the Control and High-fat groups. The level of alkaline phosphate (ALP), a bone formation marker, was significantly higher in the Green-tea group than in the Control and High-fat groups. The level of DPD crosslinks value, a bone resorption marker, was similar in the High-fat and Green-tea groups. Among the three groups, rats that received the high fat diet had significantly lower parathyroid hormones, which is related to bone metabolism. But it was not significantly different from that of the Green-tea group. In conclusion, Green-tea supplemented diet seems to have a positive effect on bone metabolism by increasing the ALP concentration and decreasing the urinary P excretion levels in female rats fed high fat diet.
(3 weeks old) were divided into the Control, High-fat, and Green-tea groups. The experimental diets were provided for 6 weeks. The serum and urine concentrations of calcium and phosphorus were determined. Serum ALP and urinary DPD crosslinks value were measured to monitor bone formation and resorption. Parathyroid hormones related to bone metabolism were determined. In summary, the weight increase at the end of the 6-week experiment was significantly higher in the high fat diet groups than in the Control group, but it was not significantly different from that of the Green-tea group. On the other hand, the serum P and urinary P excretion levels were significantly higher in rats in the Green-tea group than in the Control and High-fat groups. The level of alkaline phosphate (ALP), a bone formation marker, was significantly higher in the Green-tea group than in the Control and High-fat groups. The level of DPD crosslinks value, a bone resorption marker, was similar in the High-fat and Green-tea groups. Among the three groups, rats that received the high fat diet had significantly lower parathyroid hormones, which is related to bone metabolism. But it was not significantly different from that of the Green-tea group. In conclusion, Green-tea supplemented diet seems to have a positive effect on bone metabolism by increasing the ALP concentration and decreasing the urinary P excretion levels in female rats fed high fat diet.
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ABSTRACT
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연구방법
결과 및 고찰
요약 및 결론
REFERENCES
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