지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Background: This study aimed to evaluate the effectiveness of bazedoxifene/vitamin D combination therapy in preventing osteoporosis in postmenopausal women with osteopenia. Methods: This was an open-label, multicenter randomized-controlled, phase 4 clinical trial. Women between ages of 55 and 70 years in 9 medical tertiary centers in Korea were enrolled and assigned into 2 groups: an experiment group and a control group. The experimental group received bazedoxifene 20 mg/vitamin D 800 IU tablets for 6 months, and the control group received calcium 100 mg/vitamin D 1,000 IU tablets for 6 months. Results: A total of 142 patients (70 in the experimental group and 72 in the control group) were included. The least-square mean±standard error of change in propeptide of type I collagen after 3 months was -6.87±2.56% in the experimental group and 1.22±2.54% in the control group. After 6 months, it was -21.07±2.75% in the experimental group and 1.26±2.71% in the control group. The difference between the 2 groups was -22.33% (P<0.01). The change of C-terminal telopeptide was -12.55±4.05% in the experimental group and 11.02±4.03% in the control group after 3 months. It was -22.0±3.95% and 10.20±3.89, respectively, after 6 months. The difference between the 2 groups was -32.21% (P<0.01) after 6 months. There was no significant difference in adverse events between the 2 groups. Conclusions: The osteoporosis preventive effect and safety of administering bazedoxifene/vitamin D combination pill were confirmed in postmenopausal women who needed osteoporosis prevention.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis
Yonsei Medical Journal
2016 .01
-
Comparison of Bone Mineral Density and Markers of Bone Turnover in Osteoporotic Women after 6-Month Treatment with Alendronate or Bazedoxifene: A Randomized Controlled Trial
대한골대사학회지
2021 .01
-
Effect of Vitamin K2 Alone or in Combination on Various Bone Turnover Markers Amongst Postmenopausal Females
대한골대사학회지
2021 .01
-
Increment in vitamin D level and bone mineral accrual in children with vitamin D deficiency
Korean journal of pediatrics
2016 .01
-
Korean Society for Bone and Mineral Research Task Force Report: Perspectives on Intermittent High-dose Vitamin D Supplementation
대한골대사학회지
2017 .08
-
The Role of Vitamin D in Menopausal Medicine
고신대학교 의과대학 학술지
2016 .01
-
Vitamin D and COVID-19: Is something better than nothing?
Osteoporosis and Sarcopenia
2020 .01
-
Should We Measure Vitamin D Level?
Acute and Critical Care
2016 .01
-
Maintenance Dose of Vitamin D: How Much Is Enough?
대한골대사학회지
2018 .01
-
Calcium and Vitamin D Supplementations: 2015 Position Statement of the Korean Society for Bone and Mineral Research
대한골대사학회지
2015 .01
-
Position Statement: Vitamin D Intake to Prevent Osteoporosis and Fracture in Adults
대한골대사학회지
2022 .11
-
비타민D의 보충요법
대한의사협회지
2017 .01
-
The Effect of Education and Vitamin D Supplementation on the Achievement of Optimal Vitamin D Level in Korean Postmenopausal Women
대한골대사학회지
2019 .01
-
Vitamin D and the Immune System in Menopause: A Review
대한폐경학회지
2021 .12
-
Effects of vitamin D deficiency and daily calcium intake on bone mineral density and osteoporosis in Korean postmenopausal woman
Obstetrics & Gynecology Science
2017 .01
-
Effect of multivitamin on serum 25-hydroxy vitamin D level in postmenopausal women: A randomized, double-blind, placebo-controlled trial
Osteoporosis and Sarcopenia
2016 .01
-
Practical Vitamin D Supplementation Using Machine Learning
대한골대사학회지
2020 .01
-
The effect of metformin on vitamin B12 level in pediatric patients
Annals of Pediatirc Endocrinology & Metabolism
2022 .09
-
An interim safety analysis of hepatocellular carcinoma patients administrating oral vitamin K with or without sorafenib
Annals of Hepato-Biliary-Pancreatic Surgery
2015 .02
-
Effect of Vitamin B6 on Osteoporosis Fracture
대한골대사학회지
2023 .05
이 논문의 저자 정보
최근 본 자료
댓글(0)
0