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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 53 - 62 (10page)
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초록· 키워드
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Objective: We evaluated the combined effects of vitamin D and daily calcium intake on bone mineral density (BMD) and osteoporosis in Korean postmenopausal women.
Methods: This study is a cross-sectional study consisting of 1,921 Korean postmenopausal women aged 45 to 70 years without thyroid dysfunction, from the 2008–2011 Korean National Health and Nutrition Examination Survey. Participants were classified into six groups according to serum 25-hydroxyvitamin D (25(OH)D) levels and daily calcium intake. BMD was measured using dual-energy X-ray absorptiometry at femur and at lumbar spine, and the serum vitamin D levels were measured by radioimmunoassay.
Results: The BMD divided according to serum 25(OH)D and daily calcium intakes were not statistically different among the groups. However, when both daily calcium intake and serum 25(OH)D were not sufficient, risk of osteopenia and osteoporosis showed significant increase in both femur neck and lumbar spine (odds ratio [OR] 2.242, P=0.006; OR 3.044, P=0.001; respectively). Although daily calcium intake was sufficient, risks of osteopenia and osteoporosis significantly increased in lumbar spine group if serum 25(OH)D is <20 ng/mL (OR 2.993, P=0.006).
Conclusion: The combined effects of insufficient daily calcium intake and vitamin D deficiency may cause low BMD and increase in prevalence of osteopenia and osteoporosis in Korean postmenopausal women aged 45 to 70 years.
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참고문헌 (25)
참고문헌 신청
Agata U / 2015 / The impact of different amounts of calcium intake on bone mass and arterial calcification in ovariectomized rats / J Nutr Sci Vitaminol 61 : 391 ~ 399
Barbara Kravitz / 2016 / Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis / Yonsei Medical Journal 57 (4) : 923 ~ 927
Bauer DC / 2014 / Calcium supplements and fracture prevention / N Engl J Med 370 : 387 ~ 388
Caroli A / 2011 / Invited review: dairy intake and bone health. A viewpoint from the state of the art / J Dairy Sci 94 : 5249 ~ 5262
Cipriani C / 2013 / Effect of a single oral dose of 600,000 IU of cholecalciferol on muscle strength: a study in young women / J Endocrinol Invest 36 : 1051 ~ 1054
Barbara Kravitz / 2016 / Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis / Yonsei Medical Journal 57 (4) : 923 ~ 927
Bauer DC / 2014 / Calcium supplements and fracture prevention / N Engl J Med 370 : 387 ~ 388
Caroli A / 2011 / Invited review: dairy intake and bone health. A viewpoint from the state of the art / J Dairy Sci 94 : 5249 ~ 5262
Cipriani C / 2013 / Effect of a single oral dose of 600,000 IU of cholecalciferol on muscle strength: a study in young women / J Endocrinol Invest 36 : 1051 ~ 1054
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