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논문 기본 정보

자료유형
학술저널
저자정보
Jong Hyun Jeong (The Catholic University of Korea) Won-Myong Bahk (The Catholic University of Korea) Young Sup Woo (The Catholic University of Korea) Bo-Hyun Yoon (Naju National Hospital) Jung Goo Lee (Inje University College of Medicine) Won Kim (Inje University College of Medicine) Inki Sohn (Department of Psychiatry Keyo Hospital Keyo Medical Foundation) Sung-Yong Park (Keyo Hospital) Se-Hoon Shim (Soonchunhyang University Cheonan Hospital) Jeong Seok Seo (Chung-Ang University) IL Han Choo (Chosun University) Chan-Mo Yang (Wonkwang University) Myung Hun Jung (Hallym University Sacred Heart Hospital) Duk-In Jon (Hallym University College of Medicine) Moon Doo Kim (Jeju National University)
저널정보
대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제21권 제1호
발행연도
2023.2
수록면
32 - 48 (17page)
DOI
10.9758/cpn.2023.21.1.32

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초록· 키워드

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The objective of this study was to compare recommendations of the Korean Medication Algorithm Project for Bipolar Disorder 2022 (KMAP-BP 2022) with other recently published guidelines for treating bipolar disorder. We reviewed a total of six recently published global treatment guidelines and compared treatment recommendation of the KMAP-BP 2022 with those of other guidelines. For initial treatment of mania, there were no significant differences across treatment guidelines. All guidelines recommended mood stabilizer (MS) or atypical antipsychotic (AAP) monotherapy or a combi nation of an MS with an AAP as a first-line treatment strategy in a same degree for mania. However, the KMAP-BP 2022 recommended MS + AAP combination therapy for psychotic mania, mixed mania and psychotic depression as treatment of choice. Aripiprazole, quetiapine and olanzapine were the first-line AAPs for nearly all phases of bipolar disorder across guidelines. Some guideline suggested olanzapine is a second-line options during maintenance treatment, related to concern about long-term tolerability. Most guidelines advocated newer AAPs (asenapine, cariprazine, long-act ing injectable risperidone, and aripiprazole once monthly) as first-line treatment options for all phases while lamotrigine was recommended for depressive and maintenance phases. Lithium and valproic acid were commonly used as MSs in all phases of bipolar disorder. KMAP-BP 2022 guidelines were similar to other guidelines, reflecting current changes in prescription patterns for bipolar disorder based on accumulated research data. Strong preference for combination therapy was characteristic of KMAP-BP 2022, predominantly in the treatment of psychotic mania, mixed mania and psychotic depression.

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