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논문 기본 정보

자료유형
학술저널
저자정보
Jeong Seok Seo (Chung-Ang University) 박원명 (가톨릭대학교) Young Sup Woo (The Catholic University of Korea) Young-Min Park (Inje University College of Medicine) Won Kim (Inje University College of Medicine) Jong Hyun Jeong (The Catholic University of Korea) Se-Hoon Shim (Soonchunhyang University Cheonan Hospital) Jung Goo Lee (Inje University College of Medicine) Seung-Ho Jang (Department of Psychiatry Wonkwang University Hospital) Chan-Mo Yang (Wonkwang University) Sheng Min Wang (The Catholic University) Myung Hun Jung (Hallym University Sacred Heart Hospital) Hyung Mo Sung (Soonchunhyang University) IL Han Choo (Chosun University) Bo-Hyun Yoon (Naju National Hospital) 이상열 (원광대학교) 전덕인 (한림대학교) Kyung Joon Min (Chung-Ang University College of Medicine)
저널정보
대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제19권 제4호
발행연도
2021.11
수록면
751 - 772 (22page)
DOI
10.9758/cpn.2021.19.4.751

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초록· 키워드

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Objective: In the 19 years since the Korean College of Neuropsychopharmacology and the Korean Society for Affective Disorders developed the Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2002, four revisions have been conducted. Methods: To increase survey efficiency in this revision, to cover the general clinical practice, and to compare the results with previous KMAP-DD series, the overall structure of the questionnaire was maintained. The six sections of the questionnaire were as follows: 1) pharmacological treatment strategies for major depressive disorder (MDD) with/without psychotic features; 2) pharmacological treatment strategies for persistent depressive disorder and other depressive disorder subtypes; 3) consensus for treatment-resistant depression; 4) the choice of an antidepressant in the context of safety, adverse effects, and comorbid physical illnesses; 5) treatment strategies for special populations (children/adolescents, elderly, and women); and 6) non-pharmacological biological therapies. Recommended first-, second-, and third-line strategies were derived statistically. Results: There has been little change in the four years since KMAP-DD 2017 due to the lack of newly introduced drug or treatment strategies. However, shortened waiting time between the initial and subsequent treatments, increased preference for atypical antipsychotics (AAPs), especially aripiprazole, and combination strategies with AAPs yield an active and somewhat aggressive treatment trend in Korea. Conclusion: We expect KMAP-DD to provide clinicians with useful information about the specific strategies and medications appropriate for treating patients with MDD by bridging the gap between clinical real practice and the evidence- based world.

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