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논문 기본 정보

자료유형
학술저널
저자정보
Yong Jae Lee (Yonsei University College of Medicine) Young Shin Chung (Kyung Hee University Hospital at Gangdong Seoul Korea) Jung-Yun Lee (Yonsei University College of Medicine) Eun Ji Nam (Yonsei University College of Medicine) Sang Wun Kim (Institute of Women) Young Tae Kim (Yonsei University) Sunghoon Kim (Yonsei University)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.34 No.2
발행연도
2023.3
수록면
1 - 12 (12page)
DOI
https://doi.org/10.3802/jgo.2023.34.e17

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Objective: We evaluated the usefulness of preoperative diagnostic laparoscopy for treatmentplanning in patients with advanced-stage ovarian cancer. Methods: We retrospectively analyzed 614 patients diagnosed with advanced-stage ovariancancer between Januar y 2010 and May 2018. Primar y debulking surger y (PDS) or neoadjuvantchemotherapy (NAC) followed by inter val debulking surger y were selected based onpreoperative laparoscopic (Group 1, n=192) and computed tomography findings (Group 2,n=422). The primar y outcomes in the PDS and NAC groups were suboptimal cytoreduction(residual disease >1 cm) rate and non-high-grade serous carcinoma (non-HGSC) rate,respectively. Results: The patients who under went PDS in group 1 and group 2 were 49 (25.5%) and 279(66.1%), respectively. The suboptimal cytoreduction rate after PDS was lower in Group 1than in Group 2 (2.0% vs 11.1%, p=0.023). Moreover, Group 1 showed a tendency toward alower proportion of non-HGSC patients who under went NAC than that in Group 2 (9.1%vs. 15.4%, p=0.069). Further, Group 1 showed lower rates of postoperative morbidity thanGroup 2 (5.2% vs. 10.4%, p=0.033). However, Kaplan–Meier analysis showed no significantdifferences in sur vival outcomes between the 2 groups. Conclusion: Diagnostic laparoscopy reduced the suboptimal cytoreduction rate in the PDSgroup and the implementation rate of NAC in non-HGSC patients. Moreover, it reducedpostoperative morbidity without affecting sur vival in both groups. Thus, diagnosticlaparoscopy is a valuable diagnostic tool for determining the primar y treatment.

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