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논문 기본 정보

자료유형
학술저널
저자정보
하형인 (Pusan National University Yangsan Hospital) 김지현 (Center for Gynecologic Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea) 임지원 (Division of Cancer Registration and Surveillance, National Cancer Control Institute, National Cancer) 송용중 (부산대학교) 원영주 (연세대학교) 임명철 (국립암센터)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.35 No.1
발행연도
2024.1
수록면
1 - 10 (10page)
DOI
https://doi.org/10.3802/jgo.2024.35.e31

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초록· 키워드

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Objective: To investigate the incidence and sur vival outcomes of ovarian carcinosarcoma inKorea between 1999 and 2018. Methods: Patients diagnosed with ovarian carcinosarcoma between 1999 and 2018 wereidentified from the Korea Central Cancer Registr y (KCCR) and their information wascollected. Age-standardized incidence rates (ASRs), annual percent changes (APC), andrelative sur vival rates of ovarian carcinosarcoma were calculated and compared to those ofepithelial ovarian cancer. Results: According to the KCCR, 458 cases of ovarian carcinosarcoma were detected, andaccounted for 1.5% (458/30,679) of all epithelial ovarian cancers in Korea between 1999 and2018. The ASR of ovarian carcinosarcoma between 1999 and 2018 was 0.064 per 100,000women. The incidence rate of ovarian carcinosarcoma increased during the study period,with an ASR of 0.029 per 100,000 in 1999 and 0.073 per 100,000 in 2018. The APC of ovariancarcinosarcoma during 1999–2018 was 5.86 (p<0.001). The median overall sur vival (OS) ofpatients with ovarian carcinosarcoma was 39 months, and the 5-year OS rate was 42.5%. Among ovarian carcinosarcomas, patients with localized stages showed better clinicaloutcomes than those with regional or distant stages (5-year OS, 60.8%, 57.9%, and 32.8%,respectively; p<0.001). In addition, younger (<50 years) patients showed better OS than older(≥50 years) patients (5-year OS, 52.6% vs. 40.2%; p<0.001). Conclusion: Our nationwide registr y-based study demonstrated that the incidence of ovariancarcinosarcoma increased from 1999 to 2018 in Korea. Patients with advanced-stage diseaseand older age (≥50 years) had poorer sur vival outcomes.

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