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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 163 - 168 (6page)
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초록· 키워드
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The clinical efficacy of local ablative treatment for oligometastasis is widely accepted in most cancers. However, due to limited data, this has not been the case for hepatocellular carcinoma (HCC). Here, we report a case of pulmonary oligometastasis of a huge HCC that was treated by multimodality with liver-directed concurrent chemoradiotherapy (CCRT) plus subsequent resection of the primary lesion and local ablative radiotherapy (RT) for subsequent lung oligometastatic lesions. In this patient, liver-directed CCRT induced significant tumor shrinkage with compensatory hypertrophy of the non-tumor liver, followed by curative resection. Surgical resection of the first and second pulmonary metastatic lesions as well as local ablative RT of the third lesion achieved complete tumor regression, which led to long-term survival of 6 years. Therefore, the active use of local ablative RT requires full consideration in cases of oligometastatic HCC.
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참고문헌 (9)
참고문헌 신청
Timmerman RD / 2009 / Local surgical, ablative, and radiation treatment of metastases / CA Cancer J Clin 59:145~170
Gomez DR / 2016 / Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic nonsmall-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study / Lancet Oncol 17:1672~1682
European Association for the Study of the Liver / 2018 / EASL clinical practice guidelines : management of hepatocellular carcinoma / J Hepatol 69:182~236
Heimbach JK / 2018 / AASLD guidelines for the treatment of hepatocellular carcinoma / Hepatology 67:358~380
Kim K / 2021 / Efficacy of local therapy for oligometastatic hepatocellular carcinoma : a propensity score matched analysis / J Hepatocell Carcinoma 8:35~44
Gomez DR / 2016 / Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic nonsmall-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study / Lancet Oncol 17:1672~1682
European Association for the Study of the Liver / 2018 / EASL clinical practice guidelines : management of hepatocellular carcinoma / J Hepatol 69:182~236
Heimbach JK / 2018 / AASLD guidelines for the treatment of hepatocellular carcinoma / Hepatology 67:358~380
Kim K / 2021 / Efficacy of local therapy for oligometastatic hepatocellular carcinoma : a propensity score matched analysis / J Hepatocell Carcinoma 8:35~44
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