지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 354 - 359 (6page)
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There has been controversy regarding the first-line treatment modality for the patients who have small solitary hepatocellular carcinoma (HCC); radiofrequency ablation (RFA) or percutaneous ethanol injection (PEI), surgical hepatic resection (HR) and liver transplantation (LT). For selection of treatment modality of HCC, it should be considered of hepatic reservoir function as well as the tumor stage. If the liver function is good enough, HR may be the first choice regardless of the tumor size. However, recent studies comparing RFA with resection showed comparable outcome and similar survival rates. RFA, HR and LT provide good outcome for patients who have small HCCs. RFA would be desired in patients who have below 3.0 cm in size and low alpha-fetoprotein (<200 ng/mL). However, in small HCC with high tumor marker, HR should be considered. Better patient selection for the ‘resection first’ approach and early detection of recurrence can achieve better outcomes of the salvage LT strategy. Another benefit of resection first strategy is that it make possible to do enlist of LT for patients before recurrence at high risk of HCC recurrence after resection on the basis of pathologic aggressiveness, microvascular invasion and/or satellites nodule. They should be applied appropriately according to the tumor size, location, tumor markers and underlying liver parenchymal disease.
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등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Chen MS / 2006 / A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma / Ann Surg 243:321~328
Huang G / 2014 / Quality of life after surgical resection compared with radiofrequency ablation for small hepatocellular carcinomas / Br J Surg 101:1006~1015
Hasegawa K / 2013 / Comparison of resection and ablation for hepatocellular carcinoma : a cohort study based on a Japanese nationwide survey / J Hepatol 58:724~729
Kutlu OC / 2017 / Comparative effectiveness of first-line radiofrequency ablation versus surgical resection and transplantation for patients with early hepatocellular carcinoma / Cancer 123:1817~1827
Kim GA / 2016 / Radiofrequency ablation as an alternative to hepatic resection for single small hepatocellular carcinomas / Br J Surg 103:126~135
Huang G / 2014 / Quality of life after surgical resection compared with radiofrequency ablation for small hepatocellular carcinomas / Br J Surg 101:1006~1015
Hasegawa K / 2013 / Comparison of resection and ablation for hepatocellular carcinoma : a cohort study based on a Japanese nationwide survey / J Hepatol 58:724~729
Kutlu OC / 2017 / Comparative effectiveness of first-line radiofrequency ablation versus surgical resection and transplantation for patients with early hepatocellular carcinoma / Cancer 123:1817~1827
Kim GA / 2016 / Radiofrequency ablation as an alternative to hepatic resection for single small hepatocellular carcinomas / Br J Surg 103:126~135
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