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Combined Transarterial Chemoembolization and External Beam Radiotherapy in a Patient with Recurrent Huge Hepatocellular Carcinoma after Hepatic Resection
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논문 기본 정보

Type
Academic journal
Author
Jesang Yu (University of Ulsan) Jinhong Jung (울산대학교) Sang Min Yoon (울산대학교)
Journal
대한간암학회 Journal of Liver Cancer Journal of Liver Cancer Vol.20 No.1 KCI Accredited Journals
Published
2020.1
Pages
90 - 97 (8page)

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Combined Transarterial Chemoembolization and External Beam Radiotherapy in a Patient with Recurrent Huge Hepatocellular Carcinoma after Hepatic Resection
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The optimal treatment strategy for unresectable huge hepatocellular carcinoma (HCC) is yet to be established. Non-surgical monotherapy demonstrated insufficient oncologic outcomes in previously reported studies. To improve the clinical outcomes of unresectable huge HCC, combined locoregional treatments can be considered in selected cases. Here, we report a case of 58-year-old male patient who was treated with combined transarterial chemoembolization (TACE) and external beam radiotherapy for recurrent HCC after a previous hepatic resection. After combined TACE and radiotherapy for the intrahepatic lesion, two metastases were diagnosed in the pelvic bones and lung; each lesion was successfully treated with salvage radiotherapy. During the long-term follow-up period (around 8 years 7 months after combined TACE and radiotherapy for the recurrent huge HCC), no definite viable tumors were observed in any of the treated liver, bone, and lung lesions.
#Huge #Hepatocellular carcinoma #Therapeutic chemoembolization #Radiotherapy

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References (39)

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Bruix J / 2016 / Evidence-based diagnosis, staging, and treatment of patients with hepatocellular carcinoma / Gastroenterology 150:835~853 google schola Goh BK / 2016 / Significance of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and prognostic nutrition index as preoperative predictors of early mortality after liver resection for huge (≥10 cm) hepatocellular carcinoma / J Surg Oncol 113:621~627 google schola Hwang S / 2015 / Longterm outcome after resection of huge hepatocellular carcinoma ≥ 10 cm : single-institution experience with 471 patients / World J Surg 39:2519~2528 google schola Lee SG / 2007 / Outcome of patients with huge hepatocellular carcinoma after primary resection and treatment of recurrent lesions / Br J Surg 94:320~326 google schola Jia C / 2017 / Anatomic trisegmentectomy : an alternative treatment for huge or multiple hepatocellular carcinoma of right liver / Biomed Pharmacother 88:684~688 google schola

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