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논문 기본 정보

자료유형
학술저널
저자정보
Young-Jo Song (Konkuk University) 박우정 (건국대학교) Byung-Joo Park (Konkuk University) 이중복 (건국대학교) 박승용 (건국대학교) 송창선 (건국대학교) 이상원 (Konkuk University) Choi-Kyu Park (Kyungpook National University) 송재영 (농림축산검역본부) 최인수 (건국대학교)
저널정보
한국예방수의학회 예방수의학회지 예방수의학회지 제39권 제3호
발행연도
2015.9
수록면
130 - 133 (4page)
DOI
http://dx.doi.org/10.13041/jpvm.2015.39.3.130

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Human hepatitis B virus (HBV) infection remains a serious public health problem worldwide, as it is one of the main risk factors for hepatocellular carcinoma (HCC). Cross-species transmission of HBV has been reported in non-human primates, and pigs may also be infected with HBV or an HBV-like agent. The purpose of this study was to demonstrate the presence of HBV antigens and anti-HBV antibodies in pig sera, providing further support for the existence of HBV or an HBV-like agent in pig populations. The HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) in pig serum samples were detected using HBsAg and HBeAg ELISA Kits, respectively. Antibodies to HBsAg and the Hepatitis B core antigen (HBcAg) in serum samples were also detected using anti-HBsAg and anti-HBcAg antibody ELISA Kits, respectively. HBsAg and HBeAg were detected in 7 of 442 (1.6%) and 7 of 184 (3.8%) pig serum samples, respectively. Furthermore, antibodies specific to HBsAg and HBcAg were identified in 45 of 442 (10.2%) and 39 of 434 (9.0%) pig serum samples, respectively. However, neither HBV DNA nor antibodies to HBeAg were detected in 409 and 298 pig serum samples, respectively. HBV antigens and anti-HBV antibodies were both present in a considerable number of pig serum samples, suggesting that pigs could be infected with a variant HBV or an HBV-like agent. Further studies will be necessary to confirm cross-species infection of pigs with HBV.

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