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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 261 - 270 (10page)
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초록· 키워드
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Introduction of biologic agents to treat patients with rheumatic diseases and cancer has improved clinical outcomes. However, this advance increases the risk of hepatitis B virus (HBV) reactivation in hepatitis B surface antigen carrier and even in resolved HBV infection, which can lead to liver failure and even death. In particular, the risk of HBV reactivation is heightened by the use of B-cell depleting agents such as rituximab, high dose corticosteroid, and anti-tumor necrosis factor-α. Therefore, identification of individuals at risk, and understanding the mechanism of HBV reactivation are essential to preventing HBV reactivation before initiating immunosuppressive therapy. Here, we review the mechanism, incidence, and prevention of HBV reactivation in the setting of immunosuppression.
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등록된 정보가 없습니다.
참고문헌 (85)
참고문헌 신청
Lavanchy D / 2004 / Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures / J Viral Hepat 11:97~107
Joo KR / 1999 / Hepatitis B viral markers of Korean adults in the late 1990s:survey data of 70,347 health screenees / Korean J Gastroenterol 33:642~652
Song EY / 2009 / Prevalence of occult hepatitis B virus infection in a general adult population in Korea / Intervirology 52:57~62
Loomba R / 2017 / Hepatitis B reactivation associated with immune suppressive and biological modifier therapies:current concepts, management strategies, and future directions / Gastroenterology 152:1297~1309
Loomba R / 2008 / Systematic review : the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy / Ann Intern Med 148:519~528
Joo KR / 1999 / Hepatitis B viral markers of Korean adults in the late 1990s:survey data of 70,347 health screenees / Korean J Gastroenterol 33:642~652
Song EY / 2009 / Prevalence of occult hepatitis B virus infection in a general adult population in Korea / Intervirology 52:57~62
Loomba R / 2017 / Hepatitis B reactivation associated with immune suppressive and biological modifier therapies:current concepts, management strategies, and future directions / Gastroenterology 152:1297~1309
Loomba R / 2008 / Systematic review : the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy / Ann Intern Med 148:519~528
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