지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 14 - 19 (6page)
- DOI
- 10.14348/molcells.2015.2116
이용수
초록· 키워드
오류제보하기
Eph receptors and their ligands, ephrins, represent the largest group of the receptor tyrosine kinase (RTK) family, and they mediate numerous developmental processes in a variety of organisms. Ephrins are membrane-bound proteins that are mainly divided into two classes: A class ephrins, which are linked to the membrane by a glycosylphosphatidylinositol (GPI) linkage, and B class ephrins, which are transmembrane ligands. Based on their domain structures and affinities for ligand binding, the Eph receptors are also divided into two groups. Trans-dimerization of Eph receptors with their membrane-tethered ligands regulates cell-cell interactions and initiates bidirectional signaling pathways. These pathways are intimately involved in regulating cytoskeleton dynamics, cell migration, and alterations in cellular dynamics and shapes. The EphBs and ephrinBs are specifically localized and modified to promote higher-order clustering and initiate of bidirectional signaling. In this review, we present an in-depth overview of the structure, mechanisms, cell signaling, and functions of EphB/ephrinB in cell adhesion and migration.
목차
등록된 정보가 없습니다.
참고문헌 (74)
참고문헌 신청
Adams, R. H. / 1999 / Roles of ephrinB ligands and EphB receptors in cardiovascular development : demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis / Genes Dev 13:295~306
Adams, R. H. / 2001 / The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration / Cell 104:57~69
Arvanitis, D. N. / 2013 / Ephrin B1 maintains apical adhesion of neural progenitors / Development 140:2082~2092
Batlle, E. / 2002 / Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB / Cell 111:251~263
Becker, E. / 2000 / Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation / Mol. Cell. Biol 20:1537~1545
Adams, R. H. / 2001 / The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration / Cell 104:57~69
Arvanitis, D. N. / 2013 / Ephrin B1 maintains apical adhesion of neural progenitors / Development 140:2082~2092
Batlle, E. / 2002 / Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB / Cell 111:251~263
Becker, E. / 2000 / Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation / Mol. Cell. Biol 20:1537~1545
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Over-Expression of Ephrin-A5 in Mice Results in Decreasing the Size of Progenitor Pool through Inducing Apoptosis
Molecules and Cells
2016 .02
-
Effects of Co-Expression of Liver X Receptor β-Ligand Binding Domain with its Partner, Retinoid X Receptor α-Ligand Binding Domain, on their Solubility and Biological Activity in Escherichia coli
Journal of Microbiology and Biotechnology
2015 .01
-
Identification of an Enhancer Critical for the ephirn-A5 Gene Expression in the Posterior Region of the Mesencephalon
Molecules and Cells
2017 .06
-
Inhibitory activities of Perilla frutescens britton leaf extract against the growth, migration, and adhesion of human cancer cells
Nutrition Research and Practice
2015 .02
-
Inhibitory activities of Perilla frutescens britton leaf extract against the growth, migration, and adhesion of human cancer cells
Nutrition Research and Practice
2015 .02
-
Roles of Tsp66E and Tsp74F in border cell migration and the maintenance of border cell adhesion in Drosophila
Genes & Genomics
2015 .01
-
Compound K attenuates stromal cell-derived growth factor 1 (SDF-1)-induced migration of C6 glioma cells
Nutrition Research and Practice
2016 .06
-
Compound K attenuates stromal cell-derived growth factor 1 (SDF-1)-induced migration of C6 glioma cells
Nutrition Research and Practice
2016 .06
-
공극 규모에서의 초임계상 이산화탄소 거동 가시화를 위한 마이크로모델의 개발과 적용
대한지질학회 학술대회
2015 .10
-
Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
Nutrition Research and Practice
2020 .04
-
Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
Nutrition Research and Practice
2020 .04
-
Nanotopographical effect on cellular adhesion of stem cells
한국진공학회 학술발표회초록집
2019 .08
-
CBP7 Interferes with the Multicellular Development of Dictyostelium Cells by Inhibiting Chemoattractant-Mediated Cell Aggregation
Molecules and Cells
2018 .02
-
Anti-Inflammatory Role of TAM Family of Receptor Tyrosine Kinases Via Modulating Macrophage Function
Molecules and Cells
2019 .01
-
14-3-3 proteins contribute to leaf and root development via Brassinosteroid Insensitive 1 in Arabidopsis thaliana
Genes & Genomics
2020 .01
-
Regulatory Role of Zinc in Immune Cell Signaling
Molecules and Cells
2021 .01
-
Morphological Image Processing of Bioceramic Foam
Quantitative Bio-Science
2017 .11
-
Function and regulation of nitric oxide signaling in Drosophila
Molecules and Cells
2024 .01
-
Effects of thymosin β4-derived peptides on migration and invasion of ovarian cancer cells
Genes & Genomics
2021 .08
-
Gram-scale Synthesis of Quadruply Bonded Chromium (II) Acetate with Axial Ligands by Ligand Vapor Diffusion
Applied Science and Convergence Technology
2020 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0