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The Impact of Depression on Fracture in Elderly: A Nationwide Population-Based Retrospective-Cohort Study
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노인에서 골절에 대한 우울증의 영향: 후향적 코호트 연구

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Type
Academic journal
Author
Yu Mee Lee (한림대학교 동탄성심병원 가정의학과) Mee Young Kim (한림대학교 동탄성심병원 가정의학과) Jong Lull Yoon (한림대학교 동탄성심병원 가정의학과) Jung Jin Cho (한림대학교 동탄성심병원 가정의학과) Young Soo Ju (한림대학교 성심병원 직업환경의학과)
Journal
대한가정의학회 Korean Journal of Family Practice Korean Journal of Family Practice Vol.9 No.3 KCI Accredited Journals
Published
2019.6
Pages
277 - 283 (7page)
DOI
10.21215/kjfp.2019.9.3.277

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The Impact of Depression on Fracture in Elderly: A Nationwide Population-Based Retrospective-Cohort Study
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Background: Fractures should be actively prevented in the elderly because recovery from the damage of fractures is slow and fractures can cause both physical and psychological pain in the elderly. Previous studies have reported that depression is related to falls or low bone mineral density (BMD). This study aimed to evaluate the risk of fracture according to the depression status among the elderly. Methods: This study used the National Health Insurance Corporation cohort data to examine 96,188 elderly people aged >65 years who were examined in 2007 and 2008. The chi-square test was used to determine the general characteristics and fracture incidence in patients with depression and healthy controls, and the hazard ratio was calculated using the Cox proportional hazards model corrected for general characteristics. The Kaplan-Meier method predicted the risk of fracture in two groups during the observation period. Results: In the depressed group, 23.2% (441 of 1,904) of the patients had a fracture during the 5-year follow-up period; however, in the control group, only 17.5% (16,470 of 94,284) had a fracture (P<0.001). In addition, multivariate analysis of the adjusted variables showed that the risk of fracture in the depressed group was 1.34 times higher than that in the control group. The risk of fracture in women was 1.71 times higher than that in men, and the risk of fracture increased with age. Conclusion: The risk of fracture in the elderly who were depressed was significantly higher than that in the elderly who were not depressed.
#우울증 #우울 장애 #골절 #노인 #Depression #Depressive Disorder #Fracture #Aged

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References (29)

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Rubenstein LZ / 2006 / Falls and their prevention in elderly people : what does the evidence show / Med Clin North Am 90:807~824 google schola Cooper C / 1993 / Population-based study of survival after osteoporotic fractures / Am J Epidemiol 137:1001~1005 google schola 김이석 / 2016 / 노령 고관절 골절 예방을 위한 노력 / 대한의사협회지 59(8):631~636 dbpia Kvelde T / 2013 / Depressive symptomatology as a risk factor for falls in older people : systematic review and meta-analysis / J Am Geriatr Soc 61:694~706 google schola Kvelde T / 2010 / Physiological and cognitive mediators for the association between self-reported depressed mood and impaired choice stepping reaction time in older people / J Gerontol A Biol Sci Med Sci 65:538~544 google schola

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