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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 314 - 329 (16page)
- DOI
- 10.7762/cnr.2021.10.4.314
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초록· 키워드
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The present trial aims to evaluate a supplementation of the olive leaf extract (OLE) in adjunct with a weight loss diet on anthropometric indices, glycemic indices, lipid profile, as well as the level of adipokines, and free fatty acid in obese women. We carried out an 8-week randomized, placebo-controlled, double-blind, parallel-group, clinical trial. The participants were randomly stratified according to age and they were assigned to one of the two study groups: Standard weight loss diet (estimated daily energy requirements minus 500 kcal) + OLE supplementation (n = 35) in intervention group or Standard weight loss diet (estimated daily energy requirements minus 500 kcal) + placebo (n = 35) in placebo group. The study groups were homogeneous regarding the baseline age, height, weight, body mass index (BMI), waist circumferences, married status, and physical activity levels (p > 0.05). The results of analysis of covariance presented significant decreases in BMI, fat mass, and body weight in the OLE group compared to those in the placebo group (p < 0.05). At the end of the study, the serum levels of fasting blood sugar, insulin, low-density lipoprotein cholesterol, total cholesterol, leptin, fatty free acid, and homeostasis model assessment?insulin resistance significantly decreased, and serum levels of high-density lipoprotein cholesterol and adiponectin elevated in the intervention group (p < 0.05). Based on results it seems that the addition of OLE to a hypocaloric diet for 8-week compared with a hypocaloric diet alone may be more effective in modifying obesity and metabolic risk factors.
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참고문헌 (58)
참고문헌 신청
Atawia RT / 2019 / Mechanisms of obesity-induced metabolic and vascular dysfunctions / Front Biosci(Landmark Ed) 24:890~934
Castaner O / 2018 / The gut microbiome profile in obesity : a systematic review / Int J Endocrinol 2018:4095789
NCD Risk Factor Collaboration(NCD-RisC) / 2017 / Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016 : a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults / Lancet 390:2627~2642
Thompson WG / 2007 / Treatment of obesity / Mayo Clin Proc 82:93~101
Alamout MM / 2019 / Effectiveness of mindfulness based cognitive therapy on weight loss, improvement of hypertension and attentional bias to eating cues in overweight people / Int J Nurs Sci 7:35~40
Castaner O / 2018 / The gut microbiome profile in obesity : a systematic review / Int J Endocrinol 2018:4095789
NCD Risk Factor Collaboration(NCD-RisC) / 2017 / Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016 : a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults / Lancet 390:2627~2642
Thompson WG / 2007 / Treatment of obesity / Mayo Clin Proc 82:93~101
Alamout MM / 2019 / Effectiveness of mindfulness based cognitive therapy on weight loss, improvement of hypertension and attentional bias to eating cues in overweight people / Int J Nurs Sci 7:35~40
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