지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제19권 제4호
- 발행연도
- 2018.12
- 수록면
- 140 - 145 (6page)
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초록· 키워드
오류제보하기
A one-year-old, intact female, Maltese dog was presented with a history of anorexia and regurgitation. Thoracic radiographs and ultrasonography scans suggested an abnormal mass in the cranial mediastinal region, and computed tomography confirmed the origin of this mass. Ultrasound-guided fine needle aspiration cytology showed the presence of intermediate to large lymphoid cells showing mitotic figures. B-cell lymphoma was confirmed by the result of a polymerase chain reaction assay for antigen receptor rearrangement, therefore the patient was diagnosed with primary mediastinal large B-cell lymphoma (PMBL). The patient underwent L-CHOP (L-asparaginase, cyclophosphamide, doxorubicin, vincristine, prednisolone)-based chemotherapy, and showed complete tumoral remission from the beginning of chemotherapy. Seventy-two weeks after the completion of chemotherapy, the patient is still alive without any evidence of metastasis or relapse. A standardized treatment protocol has yet to be established for primary mediastinal lymphoma in dogs. This case report describes the complete remission of PMBL by an L-CHOP-based chemotherapy protocol in a young Maltese. Clinicians should consider that L-CHOP based chemotherapy may be useful against PMBL in dogs.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Dorn CR / 1968 / Survey of animal neoplasms in Alameda and Contra Costa Counties, California. II. Cancer morbidity in dogs and cats from Alameda County / J Natl Cancer Inst 40:307~318
Merlo DF / 2008 / Cancer incidence in pet dogs: findings of the animal tumor registry of Genoa / Italy. J Vet Intern Med 22:976~984
Villamil JA / 2009 / Hormonal and sex impact on the epidemiology of canine lymphoma / J Cancer Epidemiol :591753
Martelli M / 2015 / Primary mediastinal lymphoma: diagnosis and treatment options / Expert Rev Hematol 8:173~186
Bassan R / 2016 / Lymphoblastic lymphoma: an updated review on biology, diagnosis, and treatment / Eur J Haematol 96:447~460
Merlo DF / 2008 / Cancer incidence in pet dogs: findings of the animal tumor registry of Genoa / Italy. J Vet Intern Med 22:976~984
Villamil JA / 2009 / Hormonal and sex impact on the epidemiology of canine lymphoma / J Cancer Epidemiol :591753
Martelli M / 2015 / Primary mediastinal lymphoma: diagnosis and treatment options / Expert Rev Hematol 8:173~186
Bassan R / 2016 / Lymphoblastic lymphoma: an updated review on biology, diagnosis, and treatment / Eur J Haematol 96:447~460
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