지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 299 - 307 (9page)
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초록· 키워드
오류제보하기
Mitophagy is a process of selective removal of damaged or unnecessary mitochondria using autophagic machinery. Mitophagy plays an essential role in maintaining mitochondrial quality control and homeostasis. Mitochondrial dysfunctions and defective mitophagy in neurodegenerative diseases, cancer, and metabolic diseases indicate a close link between human disease and mitophagy. Furthermore, recent studies showing the involvement of mitophagy in differentiation and development, suggest that mitophagy may play a more active role in controlling cellular functions. A better understanding of mitophagy will provide insights about human disease and offer novel chance for treatment. This review mainly focuses on the recent implications for mitophagy in human diseases and normal physiology.
목차
등록된 정보가 없습니다.
참고문헌 (81)
참고문헌 신청
Taylor RW / 2005 / Mitochondrial DNA mutations in human disease / Nat Rev Genet 6:389~402
Kang D / 2005 / Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer / Curr Med Chem 12:429~441
Sun N / 2016 / The Mitochondrial Basis of Aging / Mol Cell 61:654~666
Baker MJ / 2014 / Mitochondrial protein quality control in health and disease / Br J Pharmacol 171:1870~1889
Burte F / 2015 / Disturbed mitochondrial dynamics and neurodegenerative disorders / Nat Rev Neurol 11:11~24
Kang D / 2005 / Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer / Curr Med Chem 12:429~441
Sun N / 2016 / The Mitochondrial Basis of Aging / Mol Cell 61:654~666
Baker MJ / 2014 / Mitochondrial protein quality control in health and disease / Br J Pharmacol 171:1870~1889
Burte F / 2015 / Disturbed mitochondrial dynamics and neurodegenerative disorders / Nat Rev Neurol 11:11~24
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