지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 679 - 688 (10page)
이용수
초록· 키워드
오류제보하기
The decrease of metabolism in the brain has been observed as the important lesions of Alzheimer’s disease (AD) from the early stages of diagnosis. The cumulative evidence has reported that the failure of mitochondria, an organelle involved in diverse biological processes as well as energy production, maybe the cause or effect of the pathogenesis of AD. Both amyloid and tau pathologies have an impact upon mitochondria through physical interaction or indirect signaling pathways, resulting in the disruption of mitochondrial function and dynamics which can trigger AD. In addition, mitochondria are involved in different biological processes depending on the specific functions of each cell type in the brain. Thus, it is necessary to understand mitochondrial dysfunction as part of the pathological phenotypes of AD according to each cell type. In this review, we summarize that 1) the effects of AD pathology inducing mitochondrial dysfunction and 2) the contribution of mitochondrial dysfunction in each cell type to AD pathogenesis.
목차
등록된 정보가 없습니다.
참고문헌 (110)
참고문헌 신청
Querfurth HW / 2010 / Alzheimer's disease / N Engl J Med 362:329~344
Cao J / 2018 / Advances in developing novel therapeutic strategies for Alzheimer's disease / Mol Neurodegener 13:64
Sanabria-Castro A / 2017 / Molecular Pathogenesis of Alzheimer's Disease : An Update / Ann Neurosci 24:46~54
Marcus C / 2014 / Brain PET in the diagnosis of Alzheimer's disease / Clin Nucl Med 39:e413~e422
Mosconi L / 2010 / Pre-clinical detection of Alzheimer's disease using FDG-PET, with or without amyloid imaging / J Alzheimers Dis 20:843~854
Cao J / 2018 / Advances in developing novel therapeutic strategies for Alzheimer's disease / Mol Neurodegener 13:64
Sanabria-Castro A / 2017 / Molecular Pathogenesis of Alzheimer's Disease : An Update / Ann Neurosci 24:46~54
Marcus C / 2014 / Brain PET in the diagnosis of Alzheimer's disease / Clin Nucl Med 39:e413~e422
Mosconi L / 2010 / Pre-clinical detection of Alzheimer's disease using FDG-PET, with or without amyloid imaging / J Alzheimers Dis 20:843~854
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Emerging perspectives on mitochondrial dysfunction and inflammation in Alzheimer’s disease
BMB Reports
2020 .01
-
Mitochondrial dysfunction and Alzheimer’s disease: prospects for therapeutic intervention
BMB Reports
2020 .01
-
An experimental approach to study the function of mitochondria in cardiomyopathy
BMB Reports
2015 .01
-
Single-cell RNA sequencing reveals B cell?related molecular biomarkers for Alzheimer’s disease
Experimental and Molecular Medicine
2021 .12
-
Application of Mitochondrial Transplantation Method in Various Indications
한국생물공학회 학술대회
2024 .09
-
Roles of mitochondria in neuronal development
BMB Reports
2018 .01
-
Mitochondrial dysfunction suppresses p53 expression via calcium-mediated nuclear factor-kB signaling in HCT116 human colorectal carcinoma cells
BMB Reports
2018 .01
-
Molecular cross talkamongthecomponentsofthe regulatory machinery of mitochondrial structure and quality control
Experimental and Molecular Medicine
2020 .01
-
Mitochondrial noncoding RNA transport
BMB Reports
2017 .01
-
Stem cell therapy for Alzheimer’s disease and related disorders: current status and future perspectives
Experimental and Molecular Medicine
2015 .01
-
microRNA-200a-3p enhances mitochondrial elongation by targeting mitochondrial fission factor
BMB Reports
2017 .01
-
Socialized mitochondria: mitonuclear crosstalk in stress
Experimental and Molecular Medicine
2024 .05
-
Techniques for investigating mitochondrial gene expression
BMB Reports
2020 .01
-
Exogenous Mitochondria-enriched Stem Cell Therapy
한국생물공학회 학술대회
2019 .10
-
Peripheral inflammatory biomarkers in Alzheimer’s disease: a brief review
BMB Reports
2020 .01
-
The coordinated regulation of mitochondrial structure and function by Drp1 for mitochondrial quality surveillance
BMB Reports
2019 .01
-
경기도 초등학교 학생수 변화 경향에 대한 조사 연구
교육녹색환경연구
2021 .01
-
Robust Isolation of Functional Mitochondria via Ultrasonic Aquatic System
한국생물공학회 학술대회
2024 .09
-
Sex differences in the progression of glucose metabolism dysfunction in Alzheimer’s disease
Experimental and Molecular Medicine
2023 .05
-
생성적 적대 신경망 기반의 3D 뇌 영상을 이용한 알츠하이머 질병 예측 모델
대한전자공학회 학술대회
2023 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0