지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 864 - 871 (8page)
- DOI
- 10.5946/ce.2021.004
이용수
초록· 키워드
오류제보하기
Background/Aims: Peptic ulcer bleeding is the most common cause of upper gastrointestinal tract bleeding. Platelet-rich plasma(PRP) enhances tissue repair, and is therefore used in various medical treatments. A combination of mechanical or electrothermalhemostasis has been recommended for upper gastrointestinal tract bleeding treatment. This study evaluated the additive efficacy ofPRP in bleeding peptic ulcer hemostasis and recovery.
Methods: Eighty patients with peptic ulcer bleeding were initially treated by hemoclipping, and were randomly chosen for eitheradditional PRP (n=40) or additional epinephrine (n=40) injections. Both groups were compared with regard to achieving hemostasisand the frequency of complications.
Results: Hemostasis was immediately achieved in both groups. Two patients (5%) in the PRP group and 8 (20%) patients in theepinephrine group experienced rebleeding after 15.9±2.8 and 12.3±3.7 days, respectively. They were managed by PRP injection inaddition to proton pump inhibitor infusion. Hemoglobin was substantially increased in the PRP-treated group with full recoveryoccurring in 60.5% compared to 31.3% of patients in the epinephrine group (p=0.001). There was no recurrent bleeding in the PRPgroup, but 4/32 (12.5%) patients in the epinephrine group exhibited rebleeding.
Conclusions: PRP showed additional benefit in reducing peptic ulcer bleeding with no reported significant complications. Clinicaltrial (NCT03733171).
목차
등록된 정보가 없습니다.
참고문헌 (33)
참고문헌 신청
Jacques J / 2014 / Endoscopic haemostasis : an overview of procedures and clinical scenarios / Dig Liver Dis 46:766~776
Everts PA / 2006 / Platelet-rich plasma and platelet gel : a review / J Extra Corpor Technol 38:174~187
Marx RE / 2004 / Platelet-rich plasma : evidence to support its use / J Oral Maxillofac Surg 62:489~496
Valeri CR / 2006 / Release of platelet-derived growth factors and proliferation of fibroblasts in the releasates from platelets stored in the liquid state at 22 degrees C after stimulation with agonists / Transfusion 46:225~229
Sunitha Raja V / 2008 / Platelet-rich fibrin : evolution of a second-generation platelet concentrate / Indian J Dent Res 19:42~46
Everts PA / 2006 / Platelet-rich plasma and platelet gel : a review / J Extra Corpor Technol 38:174~187
Marx RE / 2004 / Platelet-rich plasma : evidence to support its use / J Oral Maxillofac Surg 62:489~496
Valeri CR / 2006 / Release of platelet-derived growth factors and proliferation of fibroblasts in the releasates from platelets stored in the liquid state at 22 degrees C after stimulation with agonists / Transfusion 46:225~229
Sunitha Raja V / 2008 / Platelet-rich fibrin : evolution of a second-generation platelet concentrate / Indian J Dent Res 19:42~46
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Endoscopic Management of Peptic Ulcer Bleeding
Clinical Endoscopy
2015 .01
-
소화성 궤양 출혈의 진단과 치료
대한내과학회지
2015 .01
-
소화성 궤양 출혈의 내시경 치료
Korean Journal of Helicobacter Upper Gastrointestinal Research
2018 .01
-
Recent Developments in the Endoscopic Treatment of Patients with Peptic Ulcer Bleeding
Clinical Endoscopy
2016 .01
-
Helicobacter pylori Eradication within 120 Days Is Associated with Decreased Complicated Recurrent Peptic Ulcers in Peptic Ulcer Bleeding Patients
Gut and Liver
2015 .01
-
난치성 소화성 궤양
Korean Journal of Helicobacter Upper Gastrointestinal Research
2019 .01
-
Factors Associated with Rebleeding in Patients with Peptic Ulcer Bleeding: Analysis of the Korean Peptic Ulcer Bleeding (K-PUB) Study
Gut and Liver
2018 .01
-
Perforated Peptic Ulcer : analysis of etiology, treatment and prognosis
대한외과학회 학술대회 초록집
2017 .11
-
A Case of Transgastrostomal Endoscopy to Diagnose and Treat Gastric Ulcer Bleeding
Korean Journal of Helicobacter Upper Gastrointestinal Research
2016 .01
-
Diagnostic and Treatment Approaches for Refractory Peptic Ulcers
Clinical Endoscopy
2015 .01
-
조영제 누출이 있는 고령의 위궤양 천공 환자의 비수술적 치료 1예
대한내과학회지
2016 .01
-
Bleeding complication after endoscopic submucosal dissection of gastric neoplasm
International Journal of Gastrointestinal Intervention
2019 .01
-
Case Report for Platelet rich plasma (PRP) in 2 Dogs
WITH CAP(COMPANION ANIMAL PRACTICE)
2018 .04
-
Effectiveness of Autologous Platelet-Rich Plasma for the Healing of Ulcers after Endoscopic Submucosal Dissection
Clinical Endoscopy
2019 .01
-
Clinical Guidelines for Drug-Related Peptic Ulcer, 2020 Revised Edition
Gut and Liver
2020 .01
-
소화성 궤양 출혈의 약물 치료
Korean Journal of Helicobacter Upper Gastrointestinal Research
2018 .01
-
The IL-1B Genetic Polymorphism Is Associated with Aspirin-Induced Peptic Ulcers in a Korean Ethnic Group
Gut and Liver
2016 .01
-
National perioperative outcomes of flap coverage for pressure ulcers from 2005 to 2015 using American College of Surgeons National Surgical Quality Improvement Program
Archives of plastic surgery : APS
2018 .01
-
Vonoprazan Versus Intravenous Proton Pump Inhibitor for Prevention of High-Risk Peptic Ulcers Rebleeding After Endoscopic Hemostasis
Korean Journal of Helicobacter Upper Gastrointestinal Research
2024 .09
-
Clinical Significance and Risk Factors of Asymptomatic Peptic Ulcer Disease
Clinical Endoscopy
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0