지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 285 - 290 (6page)
이용수
초록· 키워드
오류제보하기
Refractory peptic ulcers are defined as ulcers that do not heal completely after 8 to 12 weeks of standard anti-secretory drug treatment. The most common causes of refractory ulcers are persistent Helicobacter pylori infection and use of nonsteroidal anti-inflammatory drugs (NSAIDs). Simultaneous use of two or more H. pylori diagnostic methods are recommended for increased sensitivity. Serologic tests may be useful for patients currently taking proton pump inhibitors (PPIs) or for suspected false negative results, as they are not affected by PPI use. NSAID use should be discontinued when possible. Platelet cyclooxygenase activity tests can confirm surreptitious use of NSAIDs or aspirin. Cigarette smoking can delay ulcer healing. Therefore, patients who smoke should be encouraged to quit. Zollinger-Ellison syndrome (ZES) is a rare but important cause of refractory gastroduodenal ulcers. Fasting plasma gastrin levels should be checked if ZES is suspected. If an ulcer is refractory despite a full course of standard PPI treatment, the dose should be doubled and administration of another type of PPI considered.
목차
등록된 정보가 없습니다.
참고문헌 (53)
참고문헌 신청
Lanas AI / 1995 / Risk factors associated with refractory peptic ulcers / Gastroenterology 109:1124~1133
정대영 / 2009 / 비출혈 소화성궤양 치료의 가이드라인 / 대한소화기학회지 54(5):285~297
Allahverdiyev AM / 2015 / Isolation and diagnosis of Helicobacter pylori by a new method: microcapillary culture / World J Gastroenterol 21:2622~2628
Choi YJ / 2012 / Accuracy of diagnostic tests for Helicobacter pylori in patients with peptic ulcer bleeding / Helicobacter 17:77~85
Bento-Miranda M / 2014 / Helicobacter heilmannii sensu lato: an overview of the infection in humans / World J Gastroenterol 20:17779~17787
정대영 / 2009 / 비출혈 소화성궤양 치료의 가이드라인 / 대한소화기학회지 54(5):285~297
Allahverdiyev AM / 2015 / Isolation and diagnosis of Helicobacter pylori by a new method: microcapillary culture / World J Gastroenterol 21:2622~2628
Choi YJ / 2012 / Accuracy of diagnostic tests for Helicobacter pylori in patients with peptic ulcer bleeding / Helicobacter 17:77~85
Bento-Miranda M / 2014 / Helicobacter heilmannii sensu lato: an overview of the infection in humans / World J Gastroenterol 20:17779~17787
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