지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한상부위장관 헬리코박터학회 Korean Journal of Helicobacter Upper Gastrointestinal Research Korean Journal of Helicobacter Upper Gastrointestinal Research Vol.18 No.4
- 발행연도
- 2018.1
- 수록면
- 231 - 234 (4page)
이용수
초록· 키워드
오류제보하기
Peptic ulcer bleeding (PUB) is the most common cause of non-variceal upper gastrointestinal bleeding, and its frequency has been declining over the past decades. However, mortality from PUB persists, and it is still a serious challenge in clinical practice. Although endoscopic intervention is the basic treatment modality for PUB, pharmacological therapy is an important adjunct. The emergence of proton pump inhibitors (PPIs) enables maintenance of intragastric pH ＞6, which greatly helps in the treatment of PUB. Continuous intravenous infusion of high-dose PPI reduces the re-bleeding rate, thereby helping avoid additional surgery in patients with high-risk stigmata. Moreover, administration of PPIs prior to endoscopy may reduce the need for additional endoscopic intervention. Recently introduced gastric acid suppressants, such as potassium-competitive acid blockers, have shown promising results in further treatment of PUB. (Korean J Helicobacter Up Gastrointest Res 2018;18:231-234)
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Lanas A / 2017 / Peptic ulcer disease / Lancet 390:613~624
Joon Sung Kim / 2018 / Factors Associated with Rebleeding in Patients with Peptic Ulcer Bleeding: Analysis of the Korean Peptic Ulcer Bleeding (K-PUB) Study / Gut and Liver 12(3):271~277
Rosenstock SJ / 2013 / Improving quality of care in peptic ulcer bleeding: nationwide cohort study of 13,498 consecutive patients in the Danish Clinical Register of Emergency Surgery / Am J Gastroenterol 108:1449~1457
Katschinski B / 1994 / Prognostic factors in upper gastrointestinal bleeding / Dig Dis Sci 39:706~712
Khuroo MS / 1997 / A comparison of omeprazole and placebo for bleeding peptic ulcer / N Engl J Med 336:1054~1058
Joon Sung Kim / 2018 / Factors Associated with Rebleeding in Patients with Peptic Ulcer Bleeding: Analysis of the Korean Peptic Ulcer Bleeding (K-PUB) Study / Gut and Liver 12(3):271~277
Rosenstock SJ / 2013 / Improving quality of care in peptic ulcer bleeding: nationwide cohort study of 13,498 consecutive patients in the Danish Clinical Register of Emergency Surgery / Am J Gastroenterol 108:1449~1457
Katschinski B / 1994 / Prognostic factors in upper gastrointestinal bleeding / Dig Dis Sci 39:706~712
Khuroo MS / 1997 / A comparison of omeprazole and placebo for bleeding peptic ulcer / N Engl J Med 336:1054~1058
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