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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 1,332 - 1,340 (9page)
- DOI
- 10.9799/ksfan.2017.30.6.1332
이용수
초록· 키워드
오류제보하기
In this study, we assessed antioxidant, anti-diabetic, and anti-Alzheimer activities of Opuntia ficus-indica var. saboten (OFI) at harvest time. OFIs were cultivated December 2015~November 2016 in Jeju island. The 70% ethanol extracts of OFI were used to investigate total polyphenol and flavonoid contents, antioxidant(DPPH and ABTS radical scavenging assay), anti-diabetic(yeast α-glucosidase and rat α-glucosidase inhibition assay), and anti-Alzheimer(Acetylcholinesterase and butyrylcholinesterase inhibition assay) activities. Total polyphenol and flavonoid contents of OFIs were 17.40~23.11 μg garlic acid/mg Ex and 2.17~6.22 ug (+)-catechine/mg Ex, respectively. DPPH and ABTS radical scavenging activity of OFIs were 131.98~184.90 mg ascorbic acid(AA) eq/100 g and 63.60~101.83 mg AA eq/100 g, respectively. In the anti-diabetic and anti-Alzheimer activities, 70% ethanol extracts of OFI exhibited moderate inhibition activity, compared to control (acarbose and beberine). Total polyphenol and flavonoid contents, antioxidant, anti-diabetic, and anti-Alzheimer activities were no significant differences by season, respectively. Therefore, information on comparative biological evaluations of OFI may be a beneficial in exploring functional food and drug development.
Key words: Opuntia ficus-indica, anti-diabetic activities, anti-Alzheimer activities, harvest time
목차
등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181:1199~1200
Butterweck V / 2011 / Comparative evaluation of two different Opuntia ficus-indica extracts for blood sugar lowering effects in rat / Phytother Res 25:370~375
채용병 / 2012 / 산화적 스트레스와 관련하여 신경세포의 활성에 미치는 강황 열수추출물의 영향에 대한 연구 / 생명과학회지 22(5):657~664
조정숙 / 2007 / Neuroprotective and Antioxidant Effects of the Butanol Fraction Prepared from Opuntia ficus-indica var. saboten / Biomolecules & Therapeutics 15(4):205~211
Coyle JT / 1983 / Alzheimer’s disease : A disorder of chlinergeric innervation / Science 219:1184~1190
Butterweck V / 2011 / Comparative evaluation of two different Opuntia ficus-indica extracts for blood sugar lowering effects in rat / Phytother Res 25:370~375
채용병 / 2012 / 산화적 스트레스와 관련하여 신경세포의 활성에 미치는 강황 열수추출물의 영향에 대한 연구 / 생명과학회지 22(5):657~664
조정숙 / 2007 / Neuroprotective and Antioxidant Effects of the Butanol Fraction Prepared from Opuntia ficus-indica var. saboten / Biomolecules & Therapeutics 15(4):205~211
Coyle JT / 1983 / Alzheimer’s disease : A disorder of chlinergeric innervation / Science 219:1184~1190
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