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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.7
- 수록면
- 703 - 709 (7page)
- DOI
- 10.3349/ymj.2017.58.4.703
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Purpose: This study aimed to determine whether upgrade cardiac resynchronization therapy (CRT) shows better outcomes than de novo CRT. To do so, we compared the efficacy of CRT between de novo and upgrade groups, focusing particularly on the effect of upgrade CRT on patients with pacing-induced cardiomyopathy (PiCM).
Materials and Methods: PiCM was defined as new-onset dilated cardiomyopathy following pacemaker implantation in patients with baseline normal ejection fraction ≥50%. Electro-mechanical reverse remodeling and clinical outcomes were compared among the de novo (n=62), PiCM upgrade (n=7), and non-PiCM upgrade (n=8) CRT groups.
Results: The PiCM upgrade group showed significantly greater electro-mechanical reverse remodeling than the de novo CRT or non-PiCM upgrade groups at 6-month follow-up. The rate of super-responders was significantly higher in the PiCM upgrade group than the other CRT groups. The group factor of the PiCM upgrade was identified as an independent predictor of super-responderin multivariate analysis (odds ratio 10.4, 95% confidential interval 1.08?99.4, p=0.043). During the median follow-up of 15.8 months, the PiCM upgrade group showed the lowest rate of composite clinical outcomes, including cardiac death, heart transplantation, and heart failure-related rehospitalization (p=0.059).
Conclusion: The upgrade CRT for PiCM patients showed better performance in terms of electro-mechanical reverse remodeling than de novo implantation or upgrade CRT in non-PiCM patients.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Sweeney MO / 2006 / Heart failure during cardiac pacing / Circulation 113:2082~2088
Sweeney MO / 2003 / Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction / Circulation 107:2932~2937
Cho EJ / 2016 / Paced QT interval as a risk factor for new-onset left ventricular systolic dysfunction and cardiac death after permanent pacemaker implantation / Int J Cardiol 203:158~163
Thackray SD / 2003 / The prevalence of heart failure and asymptomatic left ventricular systolic dysfunction in a typical regional pacemaker population / Eur Heart J 24:1143~1152
양지현 / 2016 / Reversal of Pacing-Induced Cardiomyopathy by Normal QRS Axis Pacing / Korean Circulation Journal 46(3):421~424
Sweeney MO / 2003 / Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction / Circulation 107:2932~2937
Cho EJ / 2016 / Paced QT interval as a risk factor for new-onset left ventricular systolic dysfunction and cardiac death after permanent pacemaker implantation / Int J Cardiol 203:158~163
Thackray SD / 2003 / The prevalence of heart failure and asymptomatic left ventricular systolic dysfunction in a typical regional pacemaker population / Eur Heart J 24:1143~1152
양지현 / 2016 / Reversal of Pacing-Induced Cardiomyopathy by Normal QRS Axis Pacing / Korean Circulation Journal 46(3):421~424
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