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논문 기본 정보

자료유형
학술저널
저자정보
Kim Joungyoun (College of Nursing Mo-Im Kim Nursing Research Institute Yonsei University) 신상준 (충북대학교) Jihyun Yoon (Department of Family Medicine Yonsei University College of Medicine) 김형섭 (Clinical Trials Center Severance Hospital Yonsei University Health System) 이재우 (충북대학교병원) Kim Ye-seul (Department of Family Medicine Chungbuk National University Hospital Cheongju Korea.) 김용환 (Department of Family Medicine Chungbuk National University Hospital) You Hyo-Sun (Department of Family Medicine Chungbuk National University Hospital Cheongju Korea.) Kang Hee-Taik (Department of Family Medicine Chungbuk National University Hospital Cheongju Korea.Department of Fa)
저널정보
한국역학회 Epidemiology and Health Epidemiology and Health Vol.44
발행연도
2022.1
수록면
1 - 8 (8page)
DOI
10.4178/epih.e2022029

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초록· 키워드

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OBJECTIVES: Opioids are prescribed to treat moderate to severe pain. We investigated recent trends in opioid (morphine, oxycodone, fentanyl, and hydromorphone) prescriptions using data from the Korean National Health Insurance Service-National Sample Cohort between 2002 and 2015. METHODS: The morphine milligram equivalent (MME) was calculated to standardize the relative potency of opioids. The number (cases) or amount (MME) of annual opioid prescriptions per 10,000 registrants was computed to analyze trends in opioid prescriptions after age standardization. Joinpoint regression analysis was conducted to calculate the annual percentage change and average annual percentage change (AAPC). RESULTS: The number (cases) of prescriptions per 10,000 registrants increased from 0.07 in 2002 to 41.23 in 2015 (AAPC, 76.0%; 95% confidence interval [CI], 61.6 to 91.7). The MME per 10,000 registrants increased from 15.06 in 2002 to 40,727.80 in 2015 (AAPC, 103.0%; 95% CI, 78.2 to 131.3). The highest AAPC of prescriptions and MME per 10,000 registrants were observed in the elderly (60-69 years) and in patients treated at general hospitals. Fentanyl prescriptions increased most rapidly among the 4 opioids. CONCLUSIONS: Consumption of opioids greatly increased in Korea over the 14-year study period.

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