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논문 기본 정보

자료유형
학술저널
저자정보
Chong Wern-Yih (Universiti Sains Malaysia) Qamarruddin Fazilawati (Hospital Tengku Ampuan Rahimah Klang) Jamalia Rahmat (Hospital Kuala Lumpur) Ismail Shatriah (Universiti Sains Malaysia)
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제36권 제3호
발행연도
2022.6
수록면
218 - 225 (8page)
DOI
10.3341/kjo.2021.0116

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Purpose: The prevalence of retinopathy of prematurity (ROP) is higher in developing countries compared to developed countries.There is limited data on vision-related quality of life (VRQoL) among children with severe type of ROP in developingcountries. This study evaluated the influence of threshold and prethreshold ROP on VRQoL in Malaysian children.Methods: Multicenter prospective cross-sectional study conducted in three tertiary hospitals in 2018 to 2019. Children lessthan 7 years old with previous ROP diagnosis were recruited. Patients with systemic comorbidities that affected vision ordaily activities were excluded. A parent or guardian completed the Children’s Visual Function Questionnaire (CVFQ) for theassessment of child’s general health, general vision, competence, personality, family impact, and treatment difficulty.Results: Eight were categorized with threshold ROP, 16 with high-risk prethreshold ROP, and 26 with low-risk prethresholdROP. Fifty age-matched controls were also included. Mean visual acuity in logarithm of the minimum angle of resolution was0.46 in the threshold, 0.08 in high-risk prethreshold, and 0.01 in low-risk prethreshold subgroups. Threshold ROP was associatedwith myopia and strabismus, and associated with poor visual acuity compared to prethreshold ROP. Mean total CVFQscore was significantly lower in the ROP group (p < 0.001) compared to the control group. Mean score and all mean subscalescores were significantly lower in the threshold subgroup compared to high-risk and low-risk prethreshold subgroups, withlowest subscale scores on general vision and general health. There was significant association between gestational age, visualacuity of the better eye, family income, and VRQoL (p < 0.05).Conclusions: ROP was associated with lower VRQoL in children born prematurely in Malaysia. The threshold ROP group is themost affected. General vision and health domains are their main difficulties encountered. Gestational age, visual acuity of thebetter eye, and family income affects the VRQoL.

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