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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 66 - 70 (5page)
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초록· 키워드
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Objective: In vitro fertilization (IVF) pregnancy is increasing. The recent reviews have reported the perinatal outcomes of IVF were preterm birth, low birth weight, small for gestational age, congenital malformations, neurologic disorders and epigenetic defects. We aimed to analyze the perinatal outcomes of IVF compared with natural pregnancy on very low birth weight infants. Methods: Our study population was derived from Neonatal Intensive Care Unit of the Gangnam CHA Medical Center from 2010 to 2014, consisting of singleton live births in very low birth weight infants. We grouped IVF group (n=24) and control group (natural pregnancy, n=112). We analyzed two groups about maternal characteristics, neonatal characteristics, and outcomes (retinopathy of prematurity [ROP], bronchopulmonary dysplasia [BPD], periventricular leukomalacia [PVL], necrotizing enterocolitis [NEC], death). Results: Maternal age was significantly older in IVF group (34.9±0.9 vs. 33.0±0.4, P=0.03). The Apgar score 1 minute of the IVF group was significantly lower than control group (4.0±0.3 vs. 4.8±0.2, P=0.03). But there were no other significant differences of neonatal morbidities. In univariate logistic regression analysis with IVF, the odds ratio of maternal age was 1.13 (95% confidence interval: 1.01-1.27, P=0.04). The relative risk of RDS, BPD, PVL, and ROP was increased, but it was not significant in univariate and multivariate logistic regression. Conclusion: As the maternal age increased, IVF pregnancy was significantly higher. The relative risk of RDS, BPD, PVL, and ROP was high in IVF group, but it was not significant in univariate and multivariate logistic regression.
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등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Edwards RG / 1980 / Establishing full-term human pregnancies using cleaving embryos grown in vitro / Br J Obstet Gynaecol 87:737~756
Kushnir VA / 2017 / Systematic review of worldwide trends in assisted reproductive technology 2004-2013 / Reprod Biol Endocrinol 15:6
Inhorn MC / 2015 / Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century / Hum Reprod Update 21:411~426
Sunderam S / 2018 / Assisted reproductive technology surveillance United States, 2015 / MMWR Surveill Summ 67:1~28
최영민 / 2013 / Current status of assisted reproductive technology in Korea, 2009 / Obstetrics & Gynecology Science 56(06):353~361
Kushnir VA / 2017 / Systematic review of worldwide trends in assisted reproductive technology 2004-2013 / Reprod Biol Endocrinol 15:6
Inhorn MC / 2015 / Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century / Hum Reprod Update 21:411~426
Sunderam S / 2018 / Assisted reproductive technology surveillance United States, 2015 / MMWR Surveill Summ 67:1~28
최영민 / 2013 / Current status of assisted reproductive technology in Korea, 2009 / Obstetrics & Gynecology Science 56(06):353~361
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